EFFECTS OF LOUD NOISE ON OXIDATION AND LIPID PEROXIDATION VARIATIONS OF LIVER TISSUE OF RABBIT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRZAEI RAMEZAN; ALAMEH A.A.; MORTAZAVI S.B.; KHAVANIN A.; KAMALIAN N.A.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Zahedan Journal of Research in Medical Sciences Year:2009 | Volume:11 | Issue:2 Page(s): 11-17

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,066

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF LOUD NOISE ON OXIDATION AND LIPID PEROXIDATION VARIATIONS OF LIVER TISSUE OF RABBIT

Author(s)

Keywords

GLUTATHIONEQ3

MALONDIALDEHYDEQ2

NOISEQ3

OXIDATIONQ3

PEROXIDATIONQ2

RABBITQ3

Abstract

Background: In today's world, NOISE is one of the major physical pollutants. The exact mechanism leading to tissue damage in loud NOISE is not clear. There are increasing evidences that show damage to cochlear tissue by NOISE is linked to cell injury induced by free radical species. The aim of this study was to investigate the relationship between change in liver tissue GLUTATHIONE (antioxidant) and MALONDIALDEHYDE (one metabolite of lipid OXIDATION) levels that occur in RABBITs which were exposed to continuous loud NOISE.Materials and Methods: This experimental study was performed on 12 white Newzeland male RABBITs in Tarbiat Modarres University in 2004. The RABBITs were assigned to the following two groups: control, and exposed to continuous loud NOISE for 96 hours (8 h/day for 12 days, SPL=110dBA and 250Hz to 20 KHz). The concentration of MALONDIALDEHYDE (MDA) and GLUTATHIONE (GSH) in liver tissue samples were measured in RABBITs after exposure to NOISE. Thiobarbituric acid reacting substance, Ellman's reagent and spectrophotometry techniques were used for this measurement. The data were statically analyzed by SPSS software and 2 groups were compared by t-test. Differences at the level of P<0.05 were considered statistically significant. Results: Comparison of the biochemical parameters of GSH and MDA measured in treated group with control indicated that antioxidant and lipid peroxidants parameters were suppressed in treated group compared to control group (p<0.05).Conclusion: Possible similarities between RABBIT and human biological system indicate the possible role of NOISE in causation of oxidative stress in context with liver tissue impairment.

Cites

No record.

References

No record.

Cite

APA: Copy

MIRZAEI, RAMEZAN, ALAMEH, A.A., MORTAZAVI, S.B., KHAVANIN, A., & KAMALIAN, N.A.. (2009). EFFECTS OF LOUD NOISE ON OXIDATION AND LIPID PEROXIDATION VARIATIONS OF LIVER TISSUE OF RABBIT. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 11(2), 11-17. SID. https://sid.ir/paper/84295/en

Vancouver: Copy

MIRZAEI RAMEZAN, ALAMEH A.A., MORTAZAVI S.B., KHAVANIN A., KAMALIAN N.A.. EFFECTS OF LOUD NOISE ON OXIDATION AND LIPID PEROXIDATION VARIATIONS OF LIVER TISSUE OF RABBIT. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2009;11(2):11-17. Available from: https://sid.ir/paper/84295/en

IEEE: Copy

RAMEZAN MIRZAEI, A.A. ALAMEH, S.B. MORTAZAVI, A. KHAVANIN, and N.A. KAMALIAN, “EFFECTS OF LOUD NOISE ON OXIDATION AND LIPID PEROXIDATION VARIATIONS OF LIVER TISSUE OF RABBIT,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 11, no. 2, pp. 11–17, 2009, [Online]. Available: https://sid.ir/paper/84295/en

Related Journal Papers