DIAGNOSTIC VALUE OF SEROLOGY VERSUS PATHOLOGY IN DIAGNOSIS OF HELICOBACTER PYLORI INFECTION

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MIRNASERI S.M.M.; YOURDKHANI F.; ALAHVERDI B.; SIAVASHI F.; KHATAMI GH.

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Journal: GOVARESH JOURNAL Year:2009 | Volume:14 | Issue:1 (SN 66) Page(s): 23-26

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Title

DIAGNOSTIC VALUE OF SEROLOGY VERSUS PATHOLOGY IN DIAGNOSIS OF HELICOBACTER PYLORI INFECTION

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Keywords

CULTUREQ3

HELICOBACTER PYLORIQ3

PATHOLOGYQ3

SEROLOGYQ3

Abstract

Introduction: HELICOBACTER PYLORI infection is likely acquired was in childhood. HELICOBACTER PYLORI is recognized as a cause of gastritis and peptic ulcer. Our objective to investigate some noninvasive tests, particularly serum Hpylori IgG, for the diagnosis of H pylori infection in comparison with the gold-standard invasive test, esophagogastroduodenoscopy with biopsy (histology and rapid urease test). Materials and Methods: We studied 100 patients (age range: 6-18 years) who underwent esophagogastroduodenoscopy with biopsy (histologic examination) for a suspicious upper gastrointestinal disease, in all of them serum Hpylori immunoglobulin G was measured and result of this were compared with those of the gold standard esopahgogastrodudenoscopy with biopsy.Results: Of 100 patients (60 males, 40 females), 91% had history of gastrointestinal disease and 29% had positive family history for gastrointestinal disease. gastritis, ulcer and erosion were found respectively in 94%, 31%, 34% of patients.Rapid urease test, SEROLOGY and histology were positive respectively in 57%, 23%, and 29% of patients. In comparison with histology sensitivity of SEROLOGY was 45% and its specificity was 71%.Conclusion: serum Hpylori IgG test has a low sensitivity and specificity in children in comparison with the gold standard invasive test.

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APA: Copy

MIRNASERI, S.M.M., YOURDKHANI, F., ALAHVERDI, B., SIAVASHI, F., & KHATAMI, GH.. (2009). DIAGNOSTIC VALUE OF SEROLOGY VERSUS PATHOLOGY IN DIAGNOSIS OF HELICOBACTER PYLORI INFECTION. GOVARESH JOURNAL, 14(1 (SN 66)), 23-26. SID. https://sid.ir/paper/86119/en

Vancouver: Copy

MIRNASERI S.M.M., YOURDKHANI F., ALAHVERDI B., SIAVASHI F., KHATAMI GH.. DIAGNOSTIC VALUE OF SEROLOGY VERSUS PATHOLOGY IN DIAGNOSIS OF HELICOBACTER PYLORI INFECTION. GOVARESH JOURNAL[Internet]. 2009;14(1 (SN 66)):23-26. Available from: https://sid.ir/paper/86119/en

IEEE: Copy

S.M.M. MIRNASERI, F. YOURDKHANI, B. ALAHVERDI, F. SIAVASHI, and GH. KHATAMI, “DIAGNOSTIC VALUE OF SEROLOGY VERSUS PATHOLOGY IN DIAGNOSIS OF HELICOBACTER PYLORI INFECTION,” GOVARESH JOURNAL, vol. 14, no. 1 (SN 66), pp. 23–26, 2009, [Online]. Available: https://sid.ir/paper/86119/en

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