RESULT AND EFFICACY OF ENDOSCOPIC ULTRASOUND GUIDED FNA IN PATIENTS WITH SOLID PANCREATIC NEOPLASM

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SHABAZKHANI B.; BAGHBANIAN M.; GHOFRANI H.; FORUTAN H.; EBRAHIMI DARYANI N.; FARAHVASH M.J.; KALANI M.; ALETAHA N.

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Journal: GOVARESH JOURNAL Year:2010 | Volume:15 | Issue:3 (SN 72) Page(s): 180-187

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Title

RESULT AND EFFICACY OF ENDOSCOPIC ULTRASOUND GUIDED FNA IN PATIENTS WITH SOLID PANCREATIC NEOPLASM

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Keywords

PANCREATIC NEOPLASMQ3

ENDOSONOGRAPHYQ3

FINE NEEDLE ASPIRATIONQ3

Abstract

Background: ENDOSONOGRAPHY is a distinct method in evaluating gastrointestinal (GI) structural lesions, particularly in the pancreatobiliary system. This procedure has made a fundamental change in the diagnosis of pancreatic mass lesions through FINE NEEDLE ASPIRATION (FNA). This study aims to evaluate the results and efficacy of endosonographic FINE NEEDLE ASPIRATION (EUS-FNA) in patients presenting with solid pancreatic masses.Methods: This was a descriptive, prospective, case series study of patients who presented with solid pancreatic masses to Imam Khomeini Hospital, Tehran, Iran over a one year period (from November 20092010-) In order to determine false negative cases, patients were followed for 6 to 12 months.Results: A total of 53 patients underwent EUS-FNA with no complications. The results were diagnostic in 46 (87%) cases. The majority of patients were male (68%) and 81% had a mass in the pancreatic head.Cytopathology results revealed 36 (68%) adenocarcinomas, 7 (13%) other malignancies, 3 (6%) benign lesions and 7 (13%) nondiagnostic cases.The frequency of nondiagnostic results was significantly more in masses smaller than 3 cm (6 vs.1, p<0.002).Patients with nondiagnostic results were younger than those with malignant cytopathologies (52±7.5 vs.66 ±7.5 years, p<0.001). Sensitivity, specificity, PPV, NPV and accuracy of EUS-FNA in adenocarcinoma cases were 88%, 100%, 100%, 70% and 90%, respectively.Conclusion: EUS-FNA is an effective and safe procedure in the histopathologic diagnosis of pancreatic tumors.

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APA: Copy

SHABAZKHANI, B., BAGHBANIAN, M., GHOFRANI, H., EBRAHIMI DARYANI, N., FARAHVASH, M.J., KALANI, M., ALETAHA, N., & FORUTAN, H.. (2010). RESULT AND EFFICACY OF ENDOSCOPIC ULTRASOUND GUIDED FNA IN PATIENTS WITH SOLID PANCREATIC NEOPLASM. GOVARESH JOURNAL, 15(3 (SN 72)), 180-187. SID. https://sid.ir/paper/86263/en

Vancouver: Copy

SHABAZKHANI B., BAGHBANIAN M., GHOFRANI H., EBRAHIMI DARYANI N., FARAHVASH M.J., KALANI M., ALETAHA N., FORUTAN H.. RESULT AND EFFICACY OF ENDOSCOPIC ULTRASOUND GUIDED FNA IN PATIENTS WITH SOLID PANCREATIC NEOPLASM. GOVARESH JOURNAL[Internet]. 2010;15(3 (SN 72)):180-187. Available from: https://sid.ir/paper/86263/en

IEEE: Copy

B. SHABAZKHANI, M. BAGHBANIAN, H. GHOFRANI, N. EBRAHIMI DARYANI, M.J. FARAHVASH, M. KALANI, N. ALETAHA, and H. FORUTAN, “RESULT AND EFFICACY OF ENDOSCOPIC ULTRASOUND GUIDED FNA IN PATIENTS WITH SOLID PANCREATIC NEOPLASM,” GOVARESH JOURNAL, vol. 15, no. 3 (SN 72), pp. 180–187, 2010, [Online]. Available: https://sid.ir/paper/86263/en

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