EFFECT OF VACCINATION AGAINST HEPATITIS B IN CASES WITH ISOLATED ANTI-HBC

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KABIR A.; KESHVARI MALIHEH; ALAVIAN S.M.

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Journal: GOVARESH JOURNAL Year:2007 | Volume:12 | Issue:2 Page(s): 86-91

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Title

EFFECT OF VACCINATION AGAINST HEPATITIS B IN CASES WITH ISOLATED ANTI-HBC

Author(s)

KABIR A. | KESHVARI MALIHEH | ALAVIAN S.M. | Issue Writer Certificate

Keywords

HEPATITIS BQ3

RECOMBINANT HEPATITIS B VACCINEQ3

IMMUNOGENECITYQ3

PERSISTENT ISOLATED ANTI-HBCQ3

Abstract

Background: 1.3% of people in Iran are positive for anti-HBc antibody. The objective of this study is to determine the rate of seroconversion in those with PERSISTENT ISOLATED ANTI-HBC after vaccination. Materials and Methods: In a quasi-experimental study, 94 persons with isolated anti-HBc antibody who were referred to Tehran Blood Transfusion Organization between 2002 and 2004 were selected through a convenient sampling. They were given recombinant HEPATITIS B vaccine on 0, 1 and 6 months. Immunization was defined by anti-HBs antibody titer ³10 mlU/mL, 1-2 months after administration of the last dose. Results: Response to HB vaccination consisted of 28%, 62% and 76% after each injection, respectively. The total response rate was 80% (n=75). Nineteen (20%) persons were negative for anti-HBs even after three doses of HB vaccination. Factors associated with decreased response to vaccination were positive anti-HBe (OR=6.4, P=0.008), history of bloodletting (OR=3.1, P=0.039) and prior history of being HBsAg positive (OR=5.6, P=0.002). Conclusion: Although there were some differences between the response rates after each vaccine injections observed in our study and similar ones, the total response was nearly the same.

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APA: Copy

KABIR, A., KESHVARI, MALIHEH, & ALAVIAN, S.M.. (2007). EFFECT OF VACCINATION AGAINST HEPATITIS B IN CASES WITH ISOLATED ANTI-HBC. GOVARESH JOURNAL, 12(2), 86-91. SID. https://sid.ir/paper/86281/en

Vancouver: Copy

KABIR A., KESHVARI MALIHEH, ALAVIAN S.M.. EFFECT OF VACCINATION AGAINST HEPATITIS B IN CASES WITH ISOLATED ANTI-HBC. GOVARESH JOURNAL[Internet]. 2007;12(2):86-91. Available from: https://sid.ir/paper/86281/en

IEEE: Copy

A. KABIR, MALIHEH KESHVARI, and S.M. ALAVIAN, “EFFECT OF VACCINATION AGAINST HEPATITIS B IN CASES WITH ISOLATED ANTI-HBC,” GOVARESH JOURNAL, vol. 12, no. 2, pp. 86–91, 2007, [Online]. Available: https://sid.ir/paper/86281/en

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