RELATIONSHIP BETWEEN FATHERS’ AGE AND INCIDENCE RATE OF SCHIZOPHRENIA

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MANTEGHI A.; ZIAEI A.; YOUSEFI A.

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Paper Information

Journal: JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH Year:2004 | Volume:5 | Issue:19-20 Page(s): 121-127

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Information Journal Paper

Title

RELATIONSHIP BETWEEN FATHERS’ AGE AND INCIDENCE RATE OF SCHIZOPHRENIA

Author(s)

MANTEGHI A. | ZIAEI A. | YOUSEFI A. | Issue Writer Certificate

Keywords

SCHIZOPHRENIAQ3

FATHER’S AGEQ4

GENETIC MUTATIONQ4

Abstract

Objectives: 1% of world population is afflicted by SCHIZOPHRENIA and its destructive consequences. Both genetic and environmental factors are supposed to have a causative role. GENETIC MUTATIONs occur under environmental influences or spontaneously. The second process occurs more frequently in the gametes of older men. So increased age of father is an important risk factor for GENETIC MUTATIONs.Method: To study this relation, we compared paternal age of schizophrenic patients with healthy subjects and other non-schizophrenic psychotic patients. Study group included 465 persons (155 in each group) diagnosed according to DSM-IV diagnostic criteria, in Ebn- e- Sina Psychiatric Hospital during a 4 month period.Findings: Average paternal age in schizophrenic, non-schizophrenic psychotic patients and healthy volunteers were: 33, 31.5 and 30 accordingly. Average maternal age was 27.6, 27.7 and 27.0 accordingly.Paternal age of schizophrenic patients was significantly higher than the other two groups (and so about paternal age higher than 40).In the previous studies both parental ages were reported to be important, but in our study there were no similar findings. Another interesting finding was a similar relation between paternal age and psychotic mood disorder in children.Results: There is an important relation between age of father and risk of SCHIZOPHRENIA in his children.

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APA: Copy

MANTEGHI, A., ZIAEI, A., & YOUSEFI, A.. (2004). RELATIONSHIP BETWEEN FATHERS’ AGE AND INCIDENCE RATE OF SCHIZOPHRENIA. JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH, 5(19-20), 121-127. SID. https://sid.ir/paper/88490/en

Vancouver: Copy

MANTEGHI A., ZIAEI A., YOUSEFI A.. RELATIONSHIP BETWEEN FATHERS’ AGE AND INCIDENCE RATE OF SCHIZOPHRENIA. JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH[Internet]. 2004;5(19-20):121-127. Available from: https://sid.ir/paper/88490/en

IEEE: Copy

A. MANTEGHI, A. ZIAEI, and A. YOUSEFI, “RELATIONSHIP BETWEEN FATHERS’ AGE AND INCIDENCE RATE OF SCHIZOPHRENIA,” JOURNAL OF FUNDAMENTALS OF MENTAL HEALTH, vol. 5, no. 19-20, pp. 121–127, 2004, [Online]. Available: https://sid.ir/paper/88490/en

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