EFFECTS OF CURCUMIN ON HISTOLOGIC LESIONS OF TESTIS INDUCED BY AFLATOXIN B1 IN RAT OFFSPRING BEFORE AND AFTER PUBERTY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NIKOOSIRJAHROMI M.; RANJBAR R.; KHAKSARMAHABADI M.; MOROVATI H.; NAJAFZADEHVARZI H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2017 | Volume:24 | Issue:6 Page(s): 41-53

Download Full-Text

Persian Verion

View:

617

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF CURCUMIN ON HISTOLOGIC LESIONS OF TESTIS INDUCED BY AFLATOXIN B1 IN RAT OFFSPRING BEFORE AND AFTER PUBERTY

Author(s)

Keywords

AFLATOXIN B1Q1

CURCUMINQ1

TESTISQ1

HISTOLOGYQ2

MORPHOMETRYQ1

Abstract

Introduction: This study was done to evaluate the use of CURCUMIN to protect testicular tissue in offspring which their mother was exposed to aflatoxin.Material & methods: Seventy adult female vistar rats were divided to control, sham and five experimental groups. Rats received serum physiology (the same volume a drugs), dimethyl sulfuxide (the same volume of drugs), AFLATOXIN B1 (0.25 mg/kg), AFLATOXIN B1 and CURCUMIN (0.25 and 50 mg/kg), AFLATOXIN B1 and CURCUMIN (0.25 and 100 mg/kg), CURCUMIN 50 mg/kg and CURCUMIN 100 mg/kg intraperitoneally in the control and experimental groups. For histologic studies, TESTIS samples were taken from male offspring at 1, 4 and 8 weeks. Samples fixed in formalin, 6µ thickness slides were prepared and stained with H&E.Findings: In all times of sampling diameter of seminiferous tubule, number of germ cells and thickness of epithelium of seminiferous tubule in rats received aflatoxin decreased compared to control but these changes were not significant. In rats which received CURCUMIN all parameters increased significantly.Discussion & conclusion: Our results showed that CURCUMIN could compensate undesirable effects of AFLATOXIN B1.

Cites

No record.

References

No record.

Cite

APA: Copy

NIKOOSIRJAHROMI, M., RANJBAR, R., KHAKSARMAHABADI, M., MOROVATI, H., & NAJAFZADEHVARZI, H.. (2017). EFFECTS OF CURCUMIN ON HISTOLOGIC LESIONS OF TESTIS INDUCED BY AFLATOXIN B1 IN RAT OFFSPRING BEFORE AND AFTER PUBERTY. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 24(6), 41-53. SID. https://sid.ir/paper/90347/en

Vancouver: Copy

NIKOOSIRJAHROMI M., RANJBAR R., KHAKSARMAHABADI M., MOROVATI H., NAJAFZADEHVARZI H.. EFFECTS OF CURCUMIN ON HISTOLOGIC LESIONS OF TESTIS INDUCED BY AFLATOXIN B1 IN RAT OFFSPRING BEFORE AND AFTER PUBERTY. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;24(6):41-53. Available from: https://sid.ir/paper/90347/en

IEEE: Copy

M. NIKOOSIRJAHROMI, R. RANJBAR, M. KHAKSARMAHABADI, H. MOROVATI, and H. NAJAFZADEHVARZI, “EFFECTS OF CURCUMIN ON HISTOLOGIC LESIONS OF TESTIS INDUCED BY AFLATOXIN B1 IN RAT OFFSPRING BEFORE AND AFTER PUBERTY,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 6, pp. 41–53, 2017, [Online]. Available: https://sid.ir/paper/90347/en

Related Journal Papers