EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP

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MANUCHEHRIAN N.; ARJOMANDI M.; BAKHSHAEI M.H.; HAJIAN P.; ALIPUR N.; FARHANCHI A.

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Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2012 | Volume:19 | Issue:4 Page(s): 1-11

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Title

EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP

Author(s)

Keywords

POST DURAL PUNCTURE HEADACHEQ2

SPINAL ANAESTHESIAQ2

INTRAVENOUS DEXAMETHASONEQ2

Abstract

Introduction: POST DURAL PUNCTURE HEADACHE (PDPH) is an important complication of spinal anesthesia, especially in young parturient women after cesarean section. The usage of glucocorticoids such as dexamethasone is a drug suggested to treat PDPH. The aim of this study was to determine the effect, of INTRAVENOUS DEXAMETHASONE in prevention of PDPH after spinal anesthesia in cesarean section.Materials & Methods: This is a double blind randomized clinical trial in which 246 cases of parturients candidated for cesarean section. Patients were divided randomly in 6 equal groups (n=41) according to the number of punctures (1, 2 or >2 punctures) and administration of 8 mg INTRAVENOUS DEXAMETHASONE. All the patients received spinal anesthesia using 75 mg of 5% lidocaine with a 25 G quincke needle. Then, the patients age, history of surgery, previous spinal anesthesia and headache, new onset and duration of PDPH and vital signs of patients were recorded. Finally the obtained data were analyzed by SPSS software.Findings: 44 (17.9%) patients out of the 246 ones were affected by headache. 12.2% of patients who had received dexamethasone and 23.6% of patients who had not received it suffered from headache, (p=0.030). The frequency of hypotension during surgery in patients who had received dexamethasone and those who had not received it were 63.4% and 76.4%, respectedly, (P=0.037).Discussion & Conclusion: Administration of intravenous prophylactic dexamethasone caused a significantly decrease in the incidence of PDPH & intraoperative hypotension. So, we suggest the use of 8 mg INTRAVENOUS DEXAMETHASONE in susceptive patients for prevention of PDPH.

Cites

EFFECT OF PROPHYLACTIC SINGLE DOSE OF DESOXY CORTICOSTERONE ACETATE ON POST DURAL PUNCTURE HEADACHE AFTER SPINAL ANESTHESIA

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APA: Copy

MANUCHEHRIAN, N., ARJOMANDI, M., BAKHSHAEI, M.H., HAJIAN, P., ALIPUR, N., & FARHANCHI, A.. (2012). EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 19(4), 1-11. SID. https://sid.ir/paper/90457/en

Vancouver: Copy

MANUCHEHRIAN N., ARJOMANDI M., BAKHSHAEI M.H., HAJIAN P., ALIPUR N., FARHANCHI A.. EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;19(4):1-11. Available from: https://sid.ir/paper/90457/en

IEEE: Copy

N. MANUCHEHRIAN, M. ARJOMANDI, M.H. BAKHSHAEI, P. HAJIAN, N. ALIPUR, and A. FARHANCHI, “EFFICACY OF PROPHYLACTIC INTRAVENOUS DEXAMETHASONE IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 4, pp. 1–11, 2012, [Online]. Available: https://sid.ir/paper/90457/en

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