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Information Journal Paper

Title

Effect of Eight Weeks of Exercise with Different Intensities on the Gene Expression of Decorin and Muscular TGF-β in the Male Adult Rats

Pages

  86-94

Abstract

 Introduction: This study aimed to investigate a period of exercise activity with different intensities on Decorin gene expression through interaction with transforming growth factor-beta (TGF-β ) in Male adult rats. Materials & Methods: This experimental study included 24 males adult Wistar rats that were divided into three groups (8 animals per group) of High-Intensity Training (HIT), Low-Intensity Training (LIT), and Control. Training groups trained for eight weeks and five days a week. The HIT group exercise program consisted of one hour of exercise for five 8-min intervals at 85%-90% Vo2max that were separated by 2-min intervals with an intensity of 50%-60% Vo2max. On the other hand, the LIT group exercise program included five 8-min intervals with an intensity of 55%-60% Vo2max, and 2-min intervals with an intensity of 45%-50% Vo2max. It should be noted that the control group received no exercise program. Findings: The results of this study showed that the expression levels of the Decorin gene in the HIT training group were significantly higher than those in the control group (P=0. 001), whereas the levels of Decorin in the LIT training groups were not significantly different from those in the control group (P=0. 11). The expression levels of the TGF-β gene in both training intensities (high-and low-intensity training, respectively) showed a significant difference, compared to the control group (P=0. 001, P=0. 18). Discussions & Conclusions: According to the results of the present study, it seems that HIT exercise can lead to a greater increase in muscle growth due to increased TGF-β-dependent myokine, compared to LIT exercise.

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    APA: Copy

    VOSADI, E., GHOLAMI, F., & MORTAZAVI, E.. (2021). Effect of Eight Weeks of Exercise with Different Intensities on the Gene Expression of Decorin and Muscular TGF-β in the Male Adult Rats. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 29(2 ), 86-94. SID. https://sid.ir/paper/950382/en

    Vancouver: Copy

    VOSADI E., GHOLAMI F., MORTAZAVI E.. Effect of Eight Weeks of Exercise with Different Intensities on the Gene Expression of Decorin and Muscular TGF-β in the Male Adult Rats. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;29(2 ):86-94. Available from: https://sid.ir/paper/950382/en

    IEEE: Copy

    E. VOSADI, F. GHOLAMI, and E. MORTAZAVI, “Effect of Eight Weeks of Exercise with Different Intensities on the Gene Expression of Decorin and Muscular TGF-β in the Male Adult Rats,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 29, no. 2 , pp. 86–94, 2021, [Online]. Available: https://sid.ir/paper/950382/en

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