The effect of endurance resistance exercise combined with Lcitrulline malate supplement onFGF, VEGF, and fatigue among young bodybuilders

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Nameni Farah; Naeini Mohammadi Mohammad Saeid

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Journal: Ebnesina Year:2020 | Volume:21 | Issue:4 (69) Page(s): 13-24

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Information Journal Paper

Title

The effect of endurance resistance exercise combined with Lcitrulline malate supplement onFGF, VEGF, and fatigue among young bodybuilders

Author(s)

Nameni Farah | Naeini Mohammadi Mohammad Saeid | Issue Writer Certificate

Keywords

Vascular Endothelial Growth Factors

Fibroblast Growth Factors

Citrulline

Boys

Abstract

Background: Citrulline malate is a non-essential alpha-amino acid supplement resulting from arginine oxidation and may cause changes in the immunity, cardiovascular, and angiogenic mechanisms. It also reduces the rating of fatigue perception. The purpose of this study was to investigate the effect of an endurance resistance exercise course combined with Citrulline malate supplement on Fibroblast Growth Factor(FGF), Vascular Endothelial Growth Factor (VEGF), and the amount of fatigue among young bodybuilders. Materials and methods: In a semi-experimental study, 40 Boys who were the members of fitness clubs were selected with simple random sampling method and were divided into four groups: control, exercise (12 weeks, four sessions per week with the intensity of 50-55% VO2max and for 75min), supplements (3000mg L-Citrulline, three times a day), and supplement + exercise. Changes in VEGF and FGF concentration (blood sample) and fatigue perception (by Borg scale) were recorded at the beginning and end of the period Results: Results of analysis of variance showed that endurance resistance training and Citrulline malate consumption significantly increased VEGF and FGF. There was also a decrease in the perception of the difficulty of the exercise in the exercise + supplement group compared to the supplement group, exercise group, and control group (p≤ 0. 05). However, Bonferroni test confirmed a significant difference only in VEGF. Conclusion: Citrulline malate and endurance resistance training with increasing VEGF and FGF enhance angiogenesis and cardiovascular activity. Therefore, this may help improve exercise performance by reducing the perception of the difficulty of the exercise.

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APA: Copy

Nameni, Farah, & Naeini Mohammadi, Mohammad Saeid. (2020). The effect of endurance resistance exercise combined with Lcitrulline malate supplement onFGF, VEGF, and fatigue among young bodybuilders. EBNESINA, 21(4 (69) ), 13-24. SID. https://sid.ir/paper/952961/en

Vancouver: Copy

Nameni Farah, Naeini Mohammadi Mohammad Saeid. The effect of endurance resistance exercise combined with Lcitrulline malate supplement onFGF, VEGF, and fatigue among young bodybuilders. EBNESINA[Internet]. 2020;21(4 (69) ):13-24. Available from: https://sid.ir/paper/952961/en

IEEE: Copy

Farah Nameni, and Mohammad Saeid Naeini Mohammadi, “The effect of endurance resistance exercise combined with Lcitrulline malate supplement onFGF, VEGF, and fatigue among young bodybuilders,” EBNESINA, vol. 21, no. 4 (69) , pp. 13–24, 2020, [Online]. Available: https://sid.ir/paper/952961/en

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