Plasmid-mediated quinolone resistance in Shigella sonnei and Shigella flexneri isolated from pediatric diarrhea

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAFARI MOHSEN; Ghasemi Kia Laila; MOHAMMADI MOHSEN; Alimadadi Hossein; ABBASI ARASH; POURNAJAF ABAZAR; Kafshgari Ramin; BORHANI KATAYOUN; Khodabandeh Mahmoud

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Pars Journal of Medical Sciences Year:2019 | Volume:17 | Issue:1 Page(s): 8-14

Download Full-Text

Persian Verion

View:

352

Download:

Cites:

Information Journal Paper

Title

Plasmid-mediated quinolone resistance in Shigella sonnei and Shigella flexneri isolated from pediatric diarrhea

Author(s)

Keywords

Quinolone

Plasmid

Shigella Sonnei

Shigella Flexneri

Children's Diarrhea

Abstract

Introduction: FluoroQuinolones are one of the most common antibiotics in the treatment of Shigella infections worldwide. The presence of Plasmids carrying Quinolone-resistance genes is one of the most important mechanisms for resistance to these drugs. Therefore, the aim of this study was to determine the presence of Quinolone resistance Plasmid genes (qnr) in Shigella Sonnei and Shigella Flexneri isolated from pediatric diarrhea. Material and methods: In a 10-month period from the beginning of June to the end of March 2012, 91 isolates of Shigella were obtained from 358 non-repetitive diarrhea samples. After identification and confirmation of Shigella isolates, antibiotic susceptibility test was performed based on the CLSI instruction. The molecular PCR test was performed to amplify qnrA, qnrB, qnrC, qnrD and qnrS genes. Results: Slide agglutination test showed that the prevalence of Shigella Sonnei and Shigella Flexneri were 69. 2% and 30. 8%, respectively. The disc diffusion test showed that all Shigella Flexneri were susceptible to levofloxacin. Most of the Shigella Sonnei were resistant to Streptomycin. The frequency of qnrA, qnrB and qnrS genes were 26. 4%, 74. 7% and 46. 2%, respectively. All strains were negative for the presence of qnrC and qnrD genes. Conclusions: The qnrB gene is the most common Plasmid-mediated Quinolone resistance (PMQR) in our treatment centers. Because of their Plasmid origin, these genes have the ability to transfer and have high ability to spread to the other isolates. Since the change in pattern of antibiotic susceptibility is occurs, perform of antibiotic susceptibility test necessary.

Cites

No record.

References

No record.

Cite

APA: Copy

JAFARI, MOHSEN, Ghasemi Kia, Laila, MOHAMMADI, MOHSEN, Alimadadi, Hossein, ABBASI, ARASH, POURNAJAF, ABAZAR, Kafshgari, Ramin, BORHANI, KATAYOUN, & Khodabandeh, Mahmoud. (2019). Plasmid-mediated quinolone resistance in Shigella sonnei and Shigella flexneri isolated from pediatric diarrhea. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 17(1 ), 8-14. SID. https://sid.ir/paper/954064/en

Vancouver: Copy

JAFARI MOHSEN, Ghasemi Kia Laila, MOHAMMADI MOHSEN, Alimadadi Hossein, ABBASI ARASH, POURNAJAF ABAZAR, Kafshgari Ramin, BORHANI KATAYOUN, Khodabandeh Mahmoud. Plasmid-mediated quinolone resistance in Shigella sonnei and Shigella flexneri isolated from pediatric diarrhea. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2019;17(1 ):8-14. Available from: https://sid.ir/paper/954064/en

IEEE: Copy

MOHSEN JAFARI, Laila Ghasemi Kia, MOHSEN MOHAMMADI, Hossein Alimadadi, ARASH ABBASI, ABAZAR POURNAJAF, Ramin Kafshgari, KATAYOUN BORHANI, and Mahmoud Khodabandeh, “Plasmid-mediated quinolone resistance in Shigella sonnei and Shigella flexneri isolated from pediatric diarrhea,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 17, no. 1 , pp. 8–14, 2019, [Online]. Available: https://sid.ir/paper/954064/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops