The Protective Effect of Cinnamon Hydroalcoholic Extract on Testicular Tissue changes and Fertility Capacity in Male Rats Exposed to Noise Stress

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PIRAMI HAMIDEH; KHAVANIN ALI; MAZAHERI ZOHREH; NADRI FARSHAD

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Journal: Journal of Birjand University of Medical Sciences Year:2018 | Volume:25 | Issue:1 Page(s): 21-30

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Title

The Protective Effect of Cinnamon Hydroalcoholic Extract on Testicular Tissue changes and Fertility Capacity in Male Rats Exposed to Noise Stress

Author(s)

PIRAMI HAMIDEH | KHAVANIN ALI | MAZAHERI ZOHREH | NADRI FARSHAD | Issue Writer Certificate

Keywords

Fertility capacityQ1

NoiseQ3

testicular tissueQ2

AntioxidantQ1

CinnamonQ2

Abstract

Background and Aim: So far, few studies have assessed the effect of Noise on Fertility capacity thus this study aimed to evaluate the possible protective effects of Cinnamon extract on testicular tissue changes and Fertility capacity in male rats exposed to Noise stress. Materials and Methods: In this experimental study, 40 male rats were randomly divided into 5 experimental groups. Group1 (control), group2 (sham), group3 (Cinnamon), group4 (Noise), group5 (Cinnamon + Noise). Rats from group 3 and 5 received Cinnamon extract (75 mg/kg) through gavage. The rats in groups 4 and 5 exposed to 100 dB Noise between 23: 00-7: 00. After 50 nights, each male rat copulated with 3 female rats and after the end of gestation period, variables such as Fertility capacity, total birth, live birth, gender and birth weight of the newborns were examined. Also testis of male rats was removed for histopathological assessment. Data were analyzed by SPSS 21. Results: The number of live newborns in group 4 compared with control group significantly reduced (P<0. 05). The weight variable between group 4 and 5 showed a significant difference (P<0. 05). Histopathological results indicated Tangible changes in exposed group 4 compared to the control group. Conclusion: The results showed that a dose of 75 mg/kg of Cinnamon extract can improve some destructive effects of Noise on testicular tissue at selected frequencies, thus, it is suggested that more studies be done on the effect of Cinnamon on Fertility capacity in a human and animal model that exposed with Noise.

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APA: Copy

PIRAMI, HAMIDEH, KHAVANIN, ALI, MAZAHERI, ZOHREH, & NADRI, FARSHAD. (2018). The Protective Effect of Cinnamon Hydroalcoholic Extract on Testicular Tissue changes and Fertility Capacity in Male Rats Exposed to Noise Stress. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 25(1 ), 21-30. SID. https://sid.ir/paper/95449/en

Vancouver: Copy

PIRAMI HAMIDEH, KHAVANIN ALI, MAZAHERI ZOHREH, NADRI FARSHAD. The Protective Effect of Cinnamon Hydroalcoholic Extract on Testicular Tissue changes and Fertility Capacity in Male Rats Exposed to Noise Stress. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;25(1 ):21-30. Available from: https://sid.ir/paper/95449/en

IEEE: Copy

HAMIDEH PIRAMI, ALI KHAVANIN, ZOHREH MAZAHERI, and FARSHAD NADRI, “The Protective Effect of Cinnamon Hydroalcoholic Extract on Testicular Tissue changes and Fertility Capacity in Male Rats Exposed to Noise Stress,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 1 , pp. 21–30, 2018, [Online]. Available: https://sid.ir/paper/95449/en

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