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Information Journal Paper

Title

Gastrointestinal Bleeding in COVID-19: A Report of Two Cases

Pages

  21-27

Keywords

Coronavirus disease 2019 (COVID-19) 

Abstract

 Background and Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) is a highly infectious viral syndrome currently threatening millions of people worldwide. It is widely recognized as a disease of the pulmonary system, presenting with fever, cough, and shortness of breath. However, a number of extra pulmonary manifestations have been described in the literature. SARS-CoV-2 is expressed in gastrointestinal (GI) epithelial cells suggesting that SARS-CoV-2 can infect and replicate in the GI tract. The most prevalent GI features of COVID-19 include abdominal pain, nausea, vomiting, and diarrhea. There is limited data regarding GI bleeding in patients with COVID-19. Subjects and Method: This single-centered, retrospective case series was conducted at Razi hospital in Khuzestan province southwestern Iran one of the provinces with highest prevalence and death due to COVID-19 disease. We recorded cases of SARS-CoV-2 infection and concurrent GI bleeding who went through surgery from September 22, 2020 to November 21, 2020. Five hundred patients where admitted to this COVID-19 center of Ahvaz city during this time line. A reverse transcription polymerase chain reaction (RT-PCR) test was performed and SARS-CoV-2 RNA was detected in the nasopharyngeal swab from these 2 patients. Results: The patients had different severities of bleeding which were associated with the severity of respiratory involvement. Both patient showed a good respond to surgery and did not showed another episode of bleeding. Conclusion: In correlation with other studies, GI bleeding in COVID-19 seems to be caused by direct virus attack leading to ischemia and Coagulopathy. Furthermore, this complication could can be related to severity of respiratory involvement.

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    APA: Copy

    Sherafatmand, Shaghayegh, Yosefzadeh, Mohsen, Shayesteh Zadeh, Behroz, & Kazemnia, Khalil. (2021). Gastrointestinal Bleeding in COVID-19: A Report of Two Cases. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 20(1 ), 21-27. SID. https://sid.ir/paper/960085/en

    Vancouver: Copy

    Sherafatmand Shaghayegh, Yosefzadeh Mohsen, Shayesteh Zadeh Behroz, Kazemnia Khalil. Gastrointestinal Bleeding in COVID-19: A Report of Two Cases. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2021;20(1 ):21-27. Available from: https://sid.ir/paper/960085/en

    IEEE: Copy

    Shaghayegh Sherafatmand, Mohsen Yosefzadeh, Behroz Shayesteh Zadeh, and Khalil Kazemnia, “Gastrointestinal Bleeding in COVID-19: A Report of Two Cases,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 20, no. 1 , pp. 21–27, 2021, [Online]. Available: https://sid.ir/paper/960085/en

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