COMPARISON OF ENDOSCOPIC AND PATHOLOGIC FINDINGS AND THEIR RELATION TO GASTERO-ESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH DYSPEPSIA

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NAJAFIAN B.; SHOHRATI M.; AMINI MOHSEN; JAHANDIDEH H.; FALAHIAN F.

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Journal: Annals of Military and Health Sciences Research Year:2005 | Volume:3 | Issue:1 (SERIAL NUMBER 9) Page(s): 481-486

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Title

COMPARISON OF ENDOSCOPIC AND PATHOLOGIC FINDINGS AND THEIR RELATION TO GASTERO-ESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH DYSPEPSIA

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Abstract

Background: Dyspepsia and gastro-esophageal reflux disease (GERD) are among the most common problems in clinical practice. Given established association between GERD and esophageal adenocarcinoma this problem has significant importance; whereas, most of symptomatic patients have non-erosive reflux disease (NERD).The aim of this study was comparison the clinical complaints with endoscopic and pathologic findings.Materials and methods: This study was done in 211 patients with clinical symptoms of dyspepsia for at least 3 months from October2003 to September2004 in Baquiatallah hospital. After completing clinical findings questionnaire, all patients underwent endoscopy and biopsy and then these methods' findings were compared.Results: Patients' mean age was 37.53 and their mean weight was 68.59. Most frequent complaints were abdominal pain (72%), heart burn (54%) and nausea (44%), respectively. Endoscopy was abnormal in 87(41.2%) patients (35.1% G I, 3.8% G II, 1.9% G III and 0.5% G IV esophagitis). 124 (58.8%) patients had normal endoscopy. Esophageal biopsy was abnormal in 54 (25.6%) patients (14.2%non-inflammatory lesions, 10.4% inflammatory lesions and 0.9% metaplasia) and 157(74.4%) patients had normal biopsy. Difference between positive endoscopy and biopsy were not significant (P=0.159).Conclusions: A considerable part of symptomatic patients have NERD. Pathology and endoscopy are not preferable to each other, so symptomatic patients should be treated regardless of para-clinic studies.

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APA: Copy

NAJAFIAN, B., SHOHRATI, M., AMINI, MOHSEN, JAHANDIDEH, H., & FALAHIAN, F.. (2005). COMPARISON OF ENDOSCOPIC AND PATHOLOGIC FINDINGS AND THEIR RELATION TO GASTERO-ESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH DYSPEPSIA. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 3(1 (SERIAL NUMBER 9)), 481-486. SID. https://sid.ir/paper/96479/en

Vancouver: Copy

NAJAFIAN B., SHOHRATI M., AMINI MOHSEN, JAHANDIDEH H., FALAHIAN F.. COMPARISON OF ENDOSCOPIC AND PATHOLOGIC FINDINGS AND THEIR RELATION TO GASTERO-ESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH DYSPEPSIA. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2005;3(1 (SERIAL NUMBER 9)):481-486. Available from: https://sid.ir/paper/96479/en

IEEE: Copy

B. NAJAFIAN, M. SHOHRATI, MOHSEN AMINI, H. JAHANDIDEH, and F. FALAHIAN, “COMPARISON OF ENDOSCOPIC AND PATHOLOGIC FINDINGS AND THEIR RELATION TO GASTERO-ESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH DYSPEPSIA,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 3, no. 1 (SERIAL NUMBER 9), pp. 481–486, 2005, [Online]. Available: https://sid.ir/paper/96479/en

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