مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

1,352
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

ALGINATE EXTRATION OF PSEUDOMONAS AEROGINOSA AND STUDY OF PENETRATUION OF ANTIBIOTIC AGENTS THROUGH ALGINATE USING A SANDWICH CUP METHOD

Pages

  695-700

Abstract

 Background: Pseudomonas aeroginosa is one of the most important oppourtunistic bacteria which produce BIOFILM. It has been reported that BIOFILM forming bacteria are more resistant to ANTIBIOTIC treatment and immunologic response. BIOFILMs, communities of cells adhering to a surface enclosed in a self-producing polymeric matrix. BIOFILMs might be responsible for 65%of bacterial infections.Materials and methods: In this study we investigated the role of the barrier formed by ALGINATE against ANTIBIOTIC penetration. Mucoid isolates of P. AERUGINOSA were collected from 2 hospitals and identified by biochemical tests. Strain M214 P. AERUGINOSA produces more BIOFILM compared with other strains. ALGINATE was extracted from mucoid- type P. AERUGINOSA (M214) with method described by Goven. We evaluated the penetration of ANTIBIOTICs macrolides (azithromycin, erythromycin), aminoglycosides (amikacin, gentamicin) lactames (imipenem, ceftazidem), fluoruqinolones (ciprofloxacin,ofloxacin) through P. AERUGINOSA (M214) ALGINATE with a sandwich cup method described by Hiromi Kumon.Results: The results indicated that macrolides demonstrated penetration rate 100%, fluroquinolones and lactames demonstrated relatively high penetration rate>85%, whereas aminoglycosides showed low penetration (amikacin=59%, gentamicin= 73%).Conclusions: In this study, the role of ALGINATE as a barrier against ANTIBIOTICs penetration was proven.

Cites

  • No record.
  • References

    Cite

    APA: Copy

    MOHAMMADI MEHR, M., ABDI AALI, A., FALAHI, Z., & MARKAZI MOGHADAM, N.. (2005). ALGINATE EXTRATION OF PSEUDOMONAS AEROGINOSA AND STUDY OF PENETRATUION OF ANTIBIOTIC AGENTS THROUGH ALGINATE USING A SANDWICH CUP METHOD. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 3(4 (SERIAL NUMBER 12)), 695-700. SID. https://sid.ir/paper/96745/en

    Vancouver: Copy

    MOHAMMADI MEHR M., ABDI AALI A., FALAHI Z., MARKAZI MOGHADAM N.. ALGINATE EXTRATION OF PSEUDOMONAS AEROGINOSA AND STUDY OF PENETRATUION OF ANTIBIOTIC AGENTS THROUGH ALGINATE USING A SANDWICH CUP METHOD. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2005;3(4 (SERIAL NUMBER 12)):695-700. Available from: https://sid.ir/paper/96745/en

    IEEE: Copy

    M. MOHAMMADI MEHR, A. ABDI AALI, Z. FALAHI, and N. MARKAZI MOGHADAM, “ALGINATE EXTRATION OF PSEUDOMONAS AEROGINOSA AND STUDY OF PENETRATUION OF ANTIBIOTIC AGENTS THROUGH ALGINATE USING A SANDWICH CUP METHOD,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 3, no. 4 (SERIAL NUMBER 12), pp. 695–700, 2005, [Online]. Available: https://sid.ir/paper/96745/en

    Related Journal Papers

    Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top