Changes of PEPCK Gene Expression in Liver Tissue and HOMAIR after High-Intensity Interval Training and Royal Jelly Consumption in Rats with Type 2 Diabetes

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Yeylaghi Ashrafi Mohammad Reza; Abednatanzi Hossein; GHAZALIAN FARSHAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2021 | Volume:31 | Issue:196 Page(s): 111-124

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Changes of PEPCK Gene Expression in Liver Tissue and HOMAIR after High-Intensity Interval Training and Royal Jelly Consumption in Rats with Type 2 Diabetes

Author(s)

Yeylaghi Ashrafi Mohammad Reza | Abednatanzi Hossein | GHAZALIAN FARSHAD | Issue Writer Certificate

Keywords

High-intensity interval training

type 2 diabetes

insulin

royal jelly

PEPCK gene

Abstract

Background and purpose: type 2 diabetes is the most common endocrine disease due to glucose intolerance and imbalance between reserves and insulin demand. The aim of this study was to investigate the interactive effect of intensity interval training and n-chromosomal royal jelly on PEPCK gene expression of hepatocytes and glucose levels and insulin resistance in type 2 diabetic rats. Materials and methods: This experimental study was done in 36 Wistar rats (4-6 weeks, 100± 20 g). After 20 weeks of high-fat diet, diabetes was induced by intraperitoneal injection of 25 mg STZ per kg body weight. The rats were treated in four groups: control (n=8), training (n=10), royal jelly (n=8), and training-royal jelly (n=10). Training protocol continued for eight weeks, including Highintensity interval training (HIIT) for five sessions per week with 2-minute alternation of 2 and 8 interval at 80 to 90% vo2max and a one-minute rest cycle at 50 to 56% vo2max. Results: Compared to the control group, aerobic exercise led to significant reductions in glucose level and insulin resistance (both P<0. 001). Exercise and royal jelly also resulted in increased PEPCK expression in hepatocytes compared to the controls. Conclusion: Improvement of glycemic profile in response to HIIT and royal jelly in diabetic rats can be attributed to changes in glucose and insulin levels and as well as changes in the expression of PEPCK hepatic gluconeogenic gene.

Cites

No record.

References

No record.

Cite

APA: Copy

Yeylaghi Ashrafi, Mohammad Reza, Abednatanzi, Hossein, & GHAZALIAN, FARSHAD. (2021). Changes of PEPCK Gene Expression in Liver Tissue and HOMAIR after High-Intensity Interval Training and Royal Jelly Consumption in Rats with Type 2 Diabetes. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 31(196 ), 111-124. SID. https://sid.ir/paper/974741/en

Vancouver: Copy

Yeylaghi Ashrafi Mohammad Reza, Abednatanzi Hossein, GHAZALIAN FARSHAD. Changes of PEPCK Gene Expression in Liver Tissue and HOMAIR after High-Intensity Interval Training and Royal Jelly Consumption in Rats with Type 2 Diabetes. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;31(196 ):111-124. Available from: https://sid.ir/paper/974741/en

IEEE: Copy

Mohammad Reza Yeylaghi Ashrafi, Hossein Abednatanzi, and FARSHAD GHAZALIAN, “Changes of PEPCK Gene Expression in Liver Tissue and HOMAIR after High-Intensity Interval Training and Royal Jelly Consumption in Rats with Type 2 Diabetes,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 31, no. 196 , pp. 111–124, 2021, [Online]. Available: https://sid.ir/paper/974741/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops