مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

High viral load detection of human Cosavirus in Iranian pediatric patients with acute gastroenteritis

Pages

  82-86

Abstract

 Aim: The present study implemented an RT-qPCR assay for the detection and quantification of human Cosavirus in Stool specimens from Pediatric Patients involved in Acute gastroenteritis. Background: Human Cosavirus is a newly recognized virus that seems to be partly related to Acute gastroenteritis in Pediatric Patients. However, the relationship between human Cosavirus and diseases in humans is unclear Methods: From January 2018 to December 2019, a total of 160 Stool samples were collected from Pediatric Patients presenting with Acute gastroenteritis in a hospital in Karaj, Iran. After viral RNA extraction, RT-qPCR was performed to amplify the 5’ UTR region of the human Cosavirus genome and viral load was analyzed. Results The human Cosavirus genomic RNA was detected in 4/160 (2. 5%) Stool samples tested. The maximum viral load was determined to be 4. 6×106 copies/ml in one sample obtained from a 4-year-old patient. Conclusion: The human Cosavirus as a new member of the Picornaviridae family was illustrated in fecal samples from Pediatric Patients with Acute gastroenteritis in Iran. This is the first documentation of human Cosavirus circulation in Iranian children.

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    APA: Copy

    Khoshbazan, Sadaf, Ivani, Zahra, MOUSAVI NASAB, SEYED DAWOOD, AHMADI, NAYEBALI, Parhiz, Aynaz, Khalesi, ahman, Firouzjani, Mohammad Hassan, GHADERI, MOSTAFA, BARATI, MARYAM, & EHSANI ARDAKANI, MOHAMMAD JAVAD. (2021). High viral load detection of human Cosavirus in Iranian pediatric patients with acute gastroenteritis. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 14(suppl1), 82-86. SID. https://sid.ir/paper/975928/en

    Vancouver: Copy

    Khoshbazan Sadaf, Ivani Zahra, MOUSAVI NASAB SEYED DAWOOD, AHMADI NAYEBALI, Parhiz Aynaz, Khalesi ahman, Firouzjani Mohammad Hassan, GHADERI MOSTAFA, BARATI MARYAM, EHSANI ARDAKANI MOHAMMAD JAVAD. High viral load detection of human Cosavirus in Iranian pediatric patients with acute gastroenteritis. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2021;14(suppl1):82-86. Available from: https://sid.ir/paper/975928/en

    IEEE: Copy

    Sadaf Khoshbazan, Zahra Ivani, SEYED DAWOOD MOUSAVI NASAB, NAYEBALI AHMADI, Aynaz Parhiz, ahman Khalesi, Mohammad Hassan Firouzjani, MOSTAFA GHADERI, MARYAM BARATI, and MOHAMMAD JAVAD EHSANI ARDAKANI, “High viral load detection of human Cosavirus in Iranian pediatric patients with acute gastroenteritis,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 14, no. suppl1, pp. 82–86, 2021, [Online]. Available: https://sid.ir/paper/975928/en

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