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Information Journal Paper

Title

Comparison of Intercostal Nerve Block with Ropivacaine and Ropivacaine-Dexmedetomidine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Randomized Clinical Trial

Pages

  0-0

Abstract

 Background: Thoracotomy is one of the most painful surgeries, and failure to alleviate patients’ pain can have dangerous consequences. Objectives: This study aimed to evaluate the addition of Dexmedetomidine to Ropivacaine in the intercostal block for Postoperative Pain control in patients undergoing Thoracotomy. Methods: In this randomized clinical trial, 74 patients aged 18 to 60 years with ASA class I or II, BMI less than 40, and no severe systemic problems referred to a teaching hospital in Ahvaz to undergo Thoracotomy were included in the study and randomly divided into two groups. After surgery, an ultrasound-guided intercostal block was done with Ropivacaine (5 cc of 0. 25% solution; group R) or Ropivacaine (5 cc of 0. 25% solution) plus Dexmedetomidine (0. 5  g/kg; group RD) per dermatome. Two dermatomes above and two dermatomes below the level of surgical incision were used. Pain, total opioid consumption, length of ICU stays, time to fi rst rescue analgesic, and time to get out of bed were compared between the two groups. Results: The intercostal block signifi cantly reduced pain in both groups (P < 0. 0001). The pain was lower in the RD group than in the R group from six hours after the intervention up to 24 hours after (P < 0. 001). The number of patients who needed rescue analgesia at 12 hours was signifi cantly lower in the RD group (P < 0. 05). The RD group also had lower total opioid consumption and a longer time to receive the fi rst rescue analgesia (P < 0. 01). There was no signifi cant diff erence between the two groups in the length of hospitalization and the time to get out of bed. Conclusions: Dexmedetomidine is an eff ective and safe choice to be used as an adjunct to Ropivacaine in ICB, and it extends the duration of analgesia in combination with Ropivacaine after Thoracotomy.

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    APA: Copy

    Mahmoudi, Kamran, Rashidi, Mahboobeh, SOLTANI, FARHAD, Savaie, Mohsen, Hedayati, Ehsan, & Rashidi, Parisa. (2021). Comparison of Intercostal Nerve Block with Ropivacaine and Ropivacaine-Dexmedetomidine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE, 11(6), 0-0. SID. https://sid.ir/paper/976236/en

    Vancouver: Copy

    Mahmoudi Kamran, Rashidi Mahboobeh, SOLTANI FARHAD, Savaie Mohsen, Hedayati Ehsan, Rashidi Parisa. Comparison of Intercostal Nerve Block with Ropivacaine and Ropivacaine-Dexmedetomidine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2021;11(6):0-0. Available from: https://sid.ir/paper/976236/en

    IEEE: Copy

    Kamran Mahmoudi, Mahboobeh Rashidi, FARHAD SOLTANI, Mohsen Savaie, Ehsan Hedayati, and Parisa Rashidi, “Comparison of Intercostal Nerve Block with Ropivacaine and Ropivacaine-Dexmedetomidine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Randomized Clinical Trial,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 11, no. 6, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/976236/en

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