مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

110
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Evaluation of some Biological Properties of Zinc Oxide (ZnO) Nanoparticles synthesized by Green Method using Aqueous Extract of Rubia tinctrom

Pages

  73-82

Abstract

 Introduction: Free radicals are molecules that have unpaired electrons in their last layer. The excessive production of free radicals causes oxidative stress. Oxidative stress thus adversely alters proteins, DNA and oxidation of the membrane phospholipids. Methods: The cytotoxic effects of zinc oxide nanoparticle were evaluated using MTT (3-(4-5dimethylthiazol-2-yl) -2, 5-difenyltetrazolium bromide) assay against MCF7 cell line breast cancer cells. Also, the Antioxidant properties of nanoparticles have been investigated using DPPH (1, 1-diphenyl-2-picyryl-hydrazyl) and ABTS (2, 2-Azino-bis (3-Ethyl benzothiazolin-6-sulfonic acid) procedure. Results: The obtain results showed that synthetized Zinc Oxide Nanoparticles had an effective Antioxidant properties in the DPPH and ABTS assay, which means that by increasing the nanoparticle concentration, the Antioxidant property increased and its IC50 values was 1000 and 125µ g/ml respectively. The result of the MTT assay was indicated that by increasing nanoparticle concentrations, the viability of MCF7 Cells was reduced and IC50 values was reported at 40µ g/ml. Conclusions: Our results shown that synthesized Zinc Oxide Nanoparticles have Antioxidant properties and in low concentrations have cytotoxicity effects on cancer cells in compare to the normal cells, which makes this nanoparticle a suitable candidate for use in inhibiting cancer cells.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    shamasi, Zahra, ESHAGHI, Ali, & HOMAYOUNI TABRIZI, MASOUD. (2019). Evaluation of some Biological Properties of Zinc Oxide (ZnO) Nanoparticles synthesized by Green Method using Aqueous Extract of Rubia tinctrom. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 11(1 ), 73-82. SID. https://sid.ir/paper/986524/en

    Vancouver: Copy

    shamasi Zahra, ESHAGHI Ali, HOMAYOUNI TABRIZI MASOUD. Evaluation of some Biological Properties of Zinc Oxide (ZnO) Nanoparticles synthesized by Green Method using Aqueous Extract of Rubia tinctrom. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;11(1 ):73-82. Available from: https://sid.ir/paper/986524/en

    IEEE: Copy

    Zahra shamasi, Ali ESHAGHI, and MASOUD HOMAYOUNI TABRIZI, “Evaluation of some Biological Properties of Zinc Oxide (ZnO) Nanoparticles synthesized by Green Method using Aqueous Extract of Rubia tinctrom,” JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, vol. 11, no. 1 , pp. 73–82, 2019, [Online]. Available: https://sid.ir/paper/986524/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button