THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DOUSTAR Y.; MOHAMMADI MOSTAFA; MOHAJERI D.; HASHEMI SEYED MEHRDAD

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2009 | Volume:19 | Issue:1 (55) Page(s): 25-32

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

818

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS

Author(s)

DOUSTAR Y. | MOHAMMADI MOSTAFA | MOHAJERI D. | HASHEMI SEYED MEHRDAD | Issue Writer Certificate

Keywords

DIABETIC HEPATOPATHYQ2

TREADMILL EXERCISEQ3

DIABETES MELLITUSQ3

Abstract

Background: Regular exercise by increasing insulin sensitivity and improving the glucose uptake and lowering body adiposity is a powerful non-pharmacological tool for prevention and treatment of DIABETES MELLITUS. DIABETIC HEPATOPATHY is the main cause of liverilure. The purpose of this study was to evaluate the effect of regular exercise on DIABETIC HEPATOPATHY.Materials and methods: In this experimental study, 56 wistar male rats with approximate age of 12 weeks and 200-300g weight were allocated into two equal groups of treatment and control. For induction of diabetes, these two groups were injected by streptozotocin (50 mg/kg) intraperitoneally. The treatment group was kept in normal conditions of management with regular exercise (treadmill) as 5 days a week, an hour every day, for 12 weeks. In control group, subjects have normal conditions without any physical activity and regular exercise. After 12 weeks, liver tissues were sampled in both groups and 5-6 micron tissue sections were prepared through H&E staining method.Results: Histopathological study in control group showed hepatosclerosis, central vein perivascular cuffing of mononuclear inflammatory cells, hepatocellular degeneration, sclerosing hyaline necrosis, apoptosis, dense perisinusoidal, and periportal and perivenular fibrosis. Mild pathological changes were observed in treatment group and significant differences were observed between two groups.Conclusion: TREADMILL EXERCISE is capable in reduction of pathological changes and improves DIABETIC HEPATOPATHY to near normal histology.

Cites

No record.

References

No record.

Cite

APA: Copy

DOUSTAR, Y., MOHAMMADI, MOSTAFA, MOHAJERI, D., & HASHEMI, SEYED MEHRDAD. (2009). THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 19(1 (55)), 25-32. SID. https://sid.ir/paper/98755/en

Vancouver: Copy

DOUSTAR Y., MOHAMMADI MOSTAFA, MOHAJERI D., HASHEMI SEYED MEHRDAD. THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2009;19(1 (55)):25-32. Available from: https://sid.ir/paper/98755/en

IEEE: Copy

Y. DOUSTAR, MOSTAFA MOHAMMADI, D. MOHAJERI, and SEYED MEHRDAD HASHEMI, “THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 19, no. 1 (55), pp. 25–32, 2009, [Online]. Available: https://sid.ir/paper/98755/en

Related Journal Papers