The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol

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Arjmand Ayat; ABEDI BAHRAM; HOSSEINI SEYED ALI

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Journal Paper

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Journal: Pharmaceutical and Biomedical Research Year:2020 | Volume:6 | Issue:4 Page(s): 261-268

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Information Journal Paper

Title

The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol

Author(s)

Arjmand Ayat | ABEDI BAHRAM | HOSSEINI SEYED ALI | Issue Writer Certificate

Keywords

Malondialdehyde

Protein carbonyl

Resistance training

Stanazolol

Heart

Abstract

Background: Consumption of anabolic steroids causes damage to various tissues, including the Heart. Objectives: This study aimed to investigate the effect of Resistance training (RT) on Malondialdehyde (MDA) and Protein carbonyl (PC) in the Heart tissue of rats exposed to stanozolol (S). Methods: In this experimental study, 18 rats with the mean age of 8 weeks and weight range of 150 to 200 g were selected and divided into three groups of 6 rats: 1. Sham (normal saline consumption) (Sh), 2. S, and 3. S+RT. For 8 weeks, the S and S+RT groups received 5 mg/ kg/d S, and the S+RT group performed 5 RT sessions per week. Measurement of MDA and PC in the Heart tissue was performed with the enzyme-linked immunosorbent assay. Results: Stanozolol had a significant effect on increasing MAD (P=0. 001) and PC (P=0. 03) in the Heart tissue. However, RT led to a decrease in MDA and PC in the Heart tissue of rats exposed to S (P=0. 001). Conclusion: It appears that S consumption leads to an increase in MDA and PC levels in the Heart tissue, while RT can improve the elevated levels of MDA and PC.

Cites

The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol

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APA: Copy

Arjmand, Ayat, ABEDI, BAHRAM, & HOSSEINI, SEYED ALI. (2020). The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol. PHARMACEUTICAL AND BIOMEDICAL RESEARCH, 6(4), 261-268. SID. https://sid.ir/paper/988471/en

Vancouver: Copy

Arjmand Ayat, ABEDI BAHRAM, HOSSEINI SEYED ALI. The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol. PHARMACEUTICAL AND BIOMEDICAL RESEARCH[Internet]. 2020;6(4):261-268. Available from: https://sid.ir/paper/988471/en

IEEE: Copy

Ayat Arjmand, BAHRAM ABEDI, and SEYED ALI HOSSEINI, “The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol,” PHARMACEUTICAL AND BIOMEDICAL RESEARCH, vol. 6, no. 4, pp. 261–268, 2020, [Online]. Available: https://sid.ir/paper/988471/en

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