The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol

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Shams Behnam; ABEDI BAHRAM; HOSSEINI SEYED ALI

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Journal Paper

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Journal: Journal of North Khorasan University of Medical Sciences Year:2022 | Volume:13 | Issue:4 Page(s): 59-65

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Information Journal Paper

Title

The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol

Author(s)

Shams Behnam | ABEDI BAHRAM | HOSSEINI SEYED ALI | Issue Writer Certificate

Keywords

Resistance Training

BDNF

Memory

Stanazolol

Abstract

Introduction Nowadays, the use of energy substances has become a complex problem in sports, in which the role of anabolic-androgenic asteroids is undeniable. The aim of this study was to evaluate the effect of a period of Resistance Training on BDNF gene expression and poor Memory in rats poisoned with anabolic steroid Stanazolol. Methods In this experimental study, 18 Sprague-Dovali rats with a weight range of 150 to 200 g and an average age of 8 weeks were randomly divided into three groups of 6 series including 1) sham (normal saline intake), 2) stanazole, 3) Stanazol was administered with Resistance Training. For eight weeks, the stanazol and Resistance Training + stanazole groups received 5 mg / kg of stanazole peritoneally daily, and the Resistance Training + stanazol group performed three sessions per week of Resistance Training. BDNF was measured in hippocampal tissue by ELISA and retention Memory using shuttle box test. Kolmogorov-Smirnov test was used to evaluate the normality of the distribution of findings and one-way analysis of variance with Tukey post hoc test in SPSS software was used to analyze the results (P≥, 0. 05). Results Stanazolol had a significant effect on reducing BDNF gene expression and nausea Memory (P ≤,0. 001). However, Resistance Training increased BDNF (P ≤,0. 001) and nausea Memory (P ≤,0. 006) in mice. Field poisoned with Stanazolol. Conclusions According to the results of the present study, it seems that Resistance Training has synergistic effects on improving BDNF and laziness in rats poisoned with stanazol.

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APA: Copy

Shams, Behnam, ABEDI, BAHRAM, & HOSSEINI, SEYED ALI. (2022). The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 13(4 ), 59-65. SID. https://sid.ir/paper/1021861/en

Vancouver: Copy

Shams Behnam, ABEDI BAHRAM, HOSSEINI SEYED ALI. The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2022;13(4 ):59-65. Available from: https://sid.ir/paper/1021861/en

IEEE: Copy

Behnam Shams, BAHRAM ABEDI, and SEYED ALI HOSSEINI, “The Effect of a Period of Resistance Training on BDNF Gene Depletion and Poor Memory of Rats Poisoned with Anabolic Steroid Stanazolol,” JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 4 , pp. 59–65, 2022, [Online]. Available: https://sid.ir/paper/1021861/en

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