IN VIVO STUDY OF THE EFFECT OF KOMBUCHA ON THE INJURED SKIN OF ADULT NMRI MICE STRAIN

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PARIVAR KAZEM; YAGHMAEI PARICHEHR; HEIDARI SHOKOUH

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Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2012 | Volume:21 | Issue:4 (66) Page(s): 262-267

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Title

IN VIVO STUDY OF THE EFFECT OF KOMBUCHA ON THE INJURED SKIN OF ADULT NMRI MICE STRAIN

Author(s)

PARIVAR KAZEM | YAGHMAEI PARICHEHR | HEIDARI SHOKOUH | Issue Writer Certificate

Keywords

KOMBUCHAQ3

INJURED SKINQ2

WOUND HEALINGQ2

Abstract

Background: KOMBUCHA is used for the treatment of several diseases, including WOUND HEALING, in traditional medicine.Due to its effective abilities, such as antibiotic activities, detoxification, and its impact on skin luminosity, we attempted to determine its effect on INJURED SKIN in in vivo condition.Materials and methods: 30 male NMRI strain were randomly assigned in control (injured skin), sham (exposed with sweet tea) and experimental (received KOMBUCHA) groups.A 3mm diameter wound with complete skin thickness was made on the back of each mouse.Treatment with KOMBUCHA was applied three times a day for 18 days.At the end of study, histological study was carried out on the under-treatment tissues.Results: Significant decrease in wound diameter was observed in experimental group compared to control group (P<0.001).Furthermore, significant increased epidermal thickness and decreased derm and hypoderm thickness were seen in experimental group compared to control group (P<0.05).Hair follicle diameter was significantly increased in experimental group compared to control group, while skin thickness diameter was in coordination with control group.Conclusion: External use of KOMBUCHA on open wound skin with complete skin thickness effectively accelerates wound-healing procedure and also increases hair follicle diameter and length in in vivo condition.

Cites

EVALUATION OF HISTOPATHOLOGICAL AND HISTOMORPHOLOGICAL EFFECTS OF KOMBUCHA EXTRACT (CAMELLIA SINENESIS) ON STOMACH SURGICAL WOUND HEALING IN ADULT MALE RAT

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APA: Copy

PARIVAR, KAZEM, YAGHMAEI, PARICHEHR, & HEIDARI, SHOKOUH. (2012). IN VIVO STUDY OF THE EFFECT OF KOMBUCHA ON THE INJURED SKIN OF ADULT NMRI MICE STRAIN. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 21(4 (66)), 262-267. SID. https://sid.ir/paper/98882/en

Vancouver: Copy

PARIVAR KAZEM, YAGHMAEI PARICHEHR, HEIDARI SHOKOUH. IN VIVO STUDY OF THE EFFECT OF KOMBUCHA ON THE INJURED SKIN OF ADULT NMRI MICE STRAIN. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2012;21(4 (66)):262-267. Available from: https://sid.ir/paper/98882/en

IEEE: Copy

KAZEM PARIVAR, PARICHEHR YAGHMAEI, and SHOKOUH HEIDARI, “IN VIVO STUDY OF THE EFFECT OF KOMBUCHA ON THE INJURED SKIN OF ADULT NMRI MICE STRAIN,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 21, no. 4 (66), pp. 262–267, 2012, [Online]. Available: https://sid.ir/paper/98882/en

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