Comparison of Saphenous Nerve Block and Oral Oxycodone for Postoperative Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial

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Nazemyanyazdi Naderali; Delavari Abasali; SAGHAFI NIA MASOUD; Emami Meibodi Mohamad Kazem

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Journal: TRAUMA MONTHLY Year:2021 | Volume:26 | Issue:5 Page(s): 265-272

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Title

Comparison of Saphenous Nerve Block and Oral Oxycodone for Postoperative Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial

Author(s)

Nazemyanyazdi Naderali | Delavari Abasali | SAGHAFI NIA MASOUD | Emami Meibodi Mohamad Kazem | Issue Writer Certificate

Keywords

Total knee arthroplasty

Post-operative pain

Saphenous Block

Oxycodone

Abstract

Introduction: Post-operative pain management following total knee replacement (TKA) is crucial. The introduction of some available, inexpensive, and effective methods for Post-operative pain management is necessary. Therefore, this randomized clinical trial was done comparing the analgesic effect of an oral low-cost drug (Oxycodone) and ultrasound-guided nerve block (saphenous nerve block) to assess the best method for Post-operative pain management after TKA surgery. Methods: This single-blind, randomized, controlled, single-center clinical trial was performed from June 2017 to June 2018. There were 80 patients undergoing TKA randomly divided into two groups,group A received a single shot ultrasound-guided saphenous nerve block and, group B took Oxycodone which started before and continued every 6 hours after surgery to control Post-operative pain. The pain score by visual analog scale (VAS), nausea-vomiting, and diclofenac use were assessed postoperatively at 2, 6, 12, and 24 hours’,post-spinal anesthesia administration. Data were analyzed by SPSS-21, Chi2, Fishers' exact test, and Mann-Whitney test were used for comparing data between the two groups. Result: The pain intensity according to the visual analog scale at 2, 6, 12, and 24 h post-operative was 1. 25±, 1. 37, 4. 12±, 1. 11, 5. 25±, 0. 89, and 4. 57±, 095 in group A, and 1. 10±, 0. 953. 77±, 0. 99, 4. 05±, 0. 78, and 2. 95±, 0. 78 in the group B, respectively,this was significantly lower in group B at 12 and 24 hours (P<0. 05). The mean diclofenac use was 87. 01±, 68. 02 mg in group B and 262. 04±, 92. 05 mg in the group A (P<0. 001). Also, the incidence of nausea and vomiting was significantly higher in group B compared to group B (P<0. 001). Conclusion: Oral Oxycodone can control Post-operative pain better than saphenous nerve block in the management of Post-operative pain and reducing total additional analgesic drug consumption. Although, adverse effects such as nausea and vomiting were lower in saphenous nerve block.

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APA: Copy

Nazemyanyazdi, Naderali, Delavari, Abasali, SAGHAFI NIA, MASOUD, & Emami Meibodi, Mohamad Kazem. (2021). Comparison of Saphenous Nerve Block and Oral Oxycodone for Postoperative Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial. TRAUMA MONTHLY, 26(5), 265-272. SID. https://sid.ir/paper/993429/en

Vancouver: Copy

Nazemyanyazdi Naderali, Delavari Abasali, SAGHAFI NIA MASOUD, Emami Meibodi Mohamad Kazem. Comparison of Saphenous Nerve Block and Oral Oxycodone for Postoperative Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial. TRAUMA MONTHLY[Internet]. 2021;26(5):265-272. Available from: https://sid.ir/paper/993429/en

IEEE: Copy

Naderali Nazemyanyazdi, Abasali Delavari, MASOUD SAGHAFI NIA, and Mohamad Kazem Emami Meibodi, “Comparison of Saphenous Nerve Block and Oral Oxycodone for Postoperative Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial,” TRAUMA MONTHLY, vol. 26, no. 5, pp. 265–272, 2021, [Online]. Available: https://sid.ir/paper/993429/en

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