Introduction: Today, the contamination caused by rapid development of industries has attracted the attention of scientific and environmental communities. This study was conducted to investigate the concentration and distribution of heavy metals in the topsoil of industrial areas in Ardakan city. Methods: In this applied research, sampling of topsoil (0-5 cm depth) was performed using five linear transects in an area of 20000 hectares. Concentrations of As, Cd, Cr, Ni, Mo, Pb, V, and Zn were measured in 45 samples based on ICP-OES method. Then, indices of Contamination Level of Heavy Metal ( ), Potential Ecological Risk of Heavy Metals ( ), and Total Potential Ecological Risk (RI) were calculated. Moreover, Pearson’ s correlation was used to assess the relationship between heavy metal’ s concentrations. Results: Results indicated that the mean concentrations of As, Cd, Cr, Mo, Ni, Pb, V, and Zn were 9. 85, 0. 31, 35. 33, 1. 001, 43. 28, 18. 51, 44. 8, and 78. 3 (mg/kg) in topsoil of studied area, respectively. Maximum concentrations of all heavy metals were found in samples collected from downstream and near the major industries except for Mo and Ni. and RI indices also showed a significant increase in downstream. Strong correlations were found between Cr-Ni, Cd-Zn, and As-Cr, which indicate that these metals probably have the same source. Conclusion: The ecological risk of the whole area was low. However, the increase of ecological risk in the surrounding and downstream of steel, pelletizing, as well as tile and ceramic factories indicated the dominant role of prevailing wind in the distribution and spread of pollution. This fact indicates the necessity of attention to the site selection studies of these industries. Furthermore, the results indicated the necessity of taking preventive measures such as phytoremediation in the downstream of the industrial areas in this region.