Iranian Journal of Breast Diseases
Year:2010 | Volume:2 | Issue:3-4|Papers Count:9

Introduction: The most common malignancy, with more than one million new case per year in the world, is breast cancer. The progression of breast cancer in human is mostly regulated with steroidal hormones such as estrogen and peptide growth factors which are interacted with epidermal growth factor 1 and 2. Hormone receptors level is low in normal breast tissue but high in two third of breast cancer.Material and Methods: In this study, 237 patients who had referred to the oncology clinic of Tabriz University of Medical Sciences with diagnosis of breast cancer (from 1382 through 1388) were involved. The variant data was extracted from the medical record. Data was analyzed by SPSS software and proper statistical examination.Results: From the total of 237 patients, 50.6% were ER+, 48.9% were PR+ and 37.1% were HER-2+. The greatest percentage of HER-2+(51.6%) was in the ages over 60 and the least in the group age 31-40 yrs. The greatest percentage of HR+(71%) was also in patients over 60 and the least (50%) in patients less than 30. 35.5% of patients in pre-menstrual period were HER-2+, at the time that HR+ percentage was 64% in LN+ patients, percentage of HER-2+ and HR+ was 35.4% and 65.4% while in LN- patients it was 39% and 61.9% respectively. The greatest positive rate of HER-2 was at stage I and HR+ was related to stage IV.Discussion: Acquired data showed to be in inverse ratio between the rate of expression of epidermal growth factor II and hormone receptors in breast cancer. 40-55% of samples with expression of epidermal growth factors lacked hormone receptors. Existence of both hormone receptors and expression of HER-2 in breast cancer are considered as important prognostic factors.

Background: Because breast are a common site of potentially fatal malignancy in women. Breast cancer is a malignant proliferation of epithelial cells lining one out of women who lives more than 80 years in north America will develop Breast cancer. Incidence of Breast cancer In middle cast women is approximately 1.5 to 1.10 of western ones. screening mammography in women over age 40 years reduces mortality of breast cancer by 33%.Material and Methods: This was across- sectional descriptive study. The target population included all of the women’s referred to Towhid hospital that were examine by an obstetrician. Mammography and X-Ray were obtained. Data was collected by questionnaire and positive diagnosis was based on standard definition of the disease with survey of the mammography, X-Ray and physical examination.Results: The mammography was done on 759 women, mean age was 41-45. Breast pain was the most common chief complain. Breast Discharge & ulcer presented in 53% of patients In mammography reports There was no abnormal findings on 68% patients and abnormal high density in 24%, Benign mass in 6% and malignant appeared mass in 0.5% of reports was presented.Conclusion: The results of this study demonstrate the need to consider the women education and implementing screening programs. Mammography and ultrasonography are the most reliable and common imaging techniques for early detection of breast lesions. Because the breast are a common site of potentially fatal malignancy in women and because they frequently provide close to underlying systemic diseases in both men and women examination of the breast is an essential part of the physical examination.

Background: This article has been studied the relationship between quality of life & hope in breast cancer patients after surgery.Material and Methods: Sample in this research was 100 women involve breast cancer & after 2 years. They refer to special Oncologist. Age of patient was 35-50. Hypotheses of research have positive significant relationship. procedure was descriptive  and analyses. Tools of research was two questioners. 1-hope of Snyder Q. (10 Q). with positive & negative orientation. 2-quality of life. with (20 Q), in dimension of physical, psychological, social and environment life. reliability was 0.78. Statistics of test was correlation & regression.Results and Conclusion: Data indicated positive and significant relationship between hope and quality of life in physical, psychological and social dimension. Result showed patient additional need to protected medicine in physical, need to supportive of family special in psychological, because they want to comeback to before of period patient.

Background: Breast cancer is the most common cancer of women and the second common cancer among Iranian women .Breast cancer screening is the best method for early detection of this cancer and decrease its prevalence. This study designed to evaluate of breast cancer screening knowledge and practice pre and post educational intervention among employed teachers in Amol city, Iran.Material and Methods: This was qusi-study on 48 employed teachers in Amol high schools .Data were gathered through random clustered sampling from different city educational area by researcher made questionnaire and checklist, before and 6 month after education and then analyzed by SPSS statistic package.Results: Statistical analyze showed that before education breast self exam, breast clinical exam and mammography knowledge and practice with correct form performed in (9.3% and 1.9%) (0 and 6.3%) (0 and 0) cases and after that reached to (39.5% and 14.8%) (40.7% and44.4%) (51.9% and 38.9%) there was a significant differences between pre and post education (P=0.000).Conclusion: According this research results, educational intervention was effective for breast cancer screening knowledge and practice, therefore widespread education and regular remember system for Breast cancer screening were recommended.

Background: Breast Cancer is a great health problem which has been growing in number now-a-day Breast self exam (BSE) is an important method for early detection so it can decease the mortality rate of this cancer. The present study a valuated Knowledge attitude and performance (KAP) of female employee of Gorgan city about BSE. Material and Methods: In this descriptive and analytical study 330 women were selected among nursing, teacher and official employee via random sampling method. Demographic data sheet and Breast self-examination knowledge, attitude and performance questionnaire were used as date gathering instruments. Statistical analysis was done by chi-square and one way ANOVA in SPSS 16 software environment.Results: Participants' age mean and standard deviation were 33.9±0.39 in range of 22-54 years. 91.8% of subjects were Domestic and 98.2% had academic education. Nurses with 67.7% and 78.6% respectively had highest knowledge and performance and 68.9% teachers had the best attitude. There were not statistically significant relation between KAP with ethnicity and educations but there were significant relation between KAP with job type and marital status. There was significant difference between age group in knowledge and performance but attitude score had not significant difference.Conclusion: This study indicates that knowledge, attitude and performance to breast self-examination is in moderate level and is needed to further educational programs.

Background: Breast cancer is a common disease in women. Detection and early diagnosis of this condition can be very effective in treating it. Mammography is currently the most effective methods of diagnosis for breast cancer.Material and Methods: We attempted to determine the masses in the mammography images. In this work, the proposed software can detect the areas around the mass completely and accurately identify and display it separately. In this method, using image processing techniques and algorithms, the mammographic images are analyzed. Noise removal and edge detection operations and the separation of areas with higher concentrations are the elements of the proposed method.Results: Because the human diagnosis and human errors do not play a role in this process, so the accuracy of the proposed method is very high. The detection rate of the proposed model is very higher than other methods reported in the valid literatures.Conclusion: The proposed algorithm has been done on 160 images in mammographic images analysis society (MIAS). The results are very acceptable, and the percentage error is less than 5 percent. High speed and free of human error was the most important factors in the proposed intelligent system.

Background: Breast cancer is the most common cancer among Iranian women. Assessing the extent of breast cancer patients' problems is one of the fundamental steps in cancer control programs. Supportive care is one of important care of women with breast cancer that will affect the survival rate of these patients. The purpose of this study was to determine quality of supportive care in breast cancer patients.Material and Methods: This descriptive study was performed in Hematology & Oncology Research Center in Tabriz University of Medical Sciences to evaluate the quality of supportive care. Sampling was based on purposive sampling and data was gathered using a questionnaire consisted of three parts, demographic characteristics, clinical variables and supportive care. Its validity and reliability were examined by face and content validity and Cronbach alpha coefficients respectively. The gathered data were analyzed with SPSS statistical software (version 14) by using the descriptive methods.Results: findings showed that the majority of the patients (63.5%) were received average supportive care. Viewpoints of patients on physical support in 51.2% and informational support in 58.6% scored average. Whereas, emotional support in (56.6%) was desirable.Conclusion: One of the fundamental role of nurses are to provide support and supportive care can influence the survival rate and quality of life in cancer patients thus, nursing program planners and managers should be explored interventions such as training courses for nurses and assess the obstacles of supportive care in nurses view to prepare them to provide special care for cancer patients.