The purpose of this study was investigation of relationship between extraversion, neuroticisim, forgiveness and Islamic coping strategies with happiness. Statistical universe was college students of Islamic Azad University of Ahvaz (16750 person), and Chamran University (12921 person). Subjects were 400 college students who selected randomly thorough stratified sampling from these universities. Instruments of this research were Oxford Happiness Questionnaire, NEO-FFI, Interpersonal forgiveness Inventory (P<0.000 - P<0.01) and Islamic coping strategies scale (P<0.000-P<0.01). Method of this research was descriptive and correlation. Data analyzad with multiple regression analysis. Results of multiple regression method indicated that there was a multiple significant correlation between four variables of predictor and dependent variable (P<0.000), and these four variables, accounted 43/4 percent of happiness variance. Results of stepwise regression showed that intotal, among four predictors variables, neuroticism, and then extraversion, were the most strong predictors for happiness. These findings emphasized the important role of these four variables that studied in this research as effective factors to improve feeling of happiness.