Today's Base of successful organizations activities has changed From production oriented to Knowledge oriented. Unlike the industrial economy in the knowledge economy, knowledge or intellectual capital as a factor of wealth production compared with other as sets to gain competitive advantage and organizational goals play a significant role. Several reasons for the importance and necessity of intellectual capital, are: First, according to the non profits Ector strategic focus on intellectual resources, and More will be accepting challenges imposed by the external environments. Second, intellectual capital is a key driver in driving organizational performance and competitiveness. Moreover, instead of using the traditional scale, the intellectual capital empowers to the connection point between universities and organizations based on a common language, that it’s the most interesting reason for measuring intellectual capital. The final reason intellectual capital will playa key role in the strategic management of human resources. on the other hand, today managers seeking to achieve a comprehensive, reliable and flexible approach in order to evaluate the performance of the organization, For this purpose the balanced score card model is used. This paper analyzes the impact of intellectual capital with mediating cultural capital and knowledge management practices on organizational performance in Isfahan Gas Company. The significance of this paper is to consider the five most important organizational variable, namely human capital, structural capital, cultural capital, the KM Practice, and organizational performance, and the other to pay attention to the performance of a comprehensive model (Model BSC), which to get her makes this study different from previous studies. Data was collected through questionnaires that the study had good reliability and validity have been done. The questionnaire was completed by 30 middle and an excellent managers company to have been selected by convenience sampling, data distribution and structural equation techniques (PLS) were analyzed. The results of the analysis of the data shows that the model study has been the perfect fit. In this model, human and structural capital have direct and positive impact on the organization's performance, On the other hand, this components as well as in directly through the mediation of KM practices and cultural capital on organizational performance is positive. Thus, all hypotheses were confirmed.