In this study, effect of astaxanthin on growth, pigmentation and blood factors were studied in rainbow trout weighted average (93±0.64g) in pools of Mr. Sarshar farm that was located in the 3000 Road of Tonekabone region of Mazandaran province for 8 weeks. Two treatments and three replicates were employed as follows: Treatment A: fed with commercial diet (control), treatment B: 41mg/kg astaxanthin. All treatments were fed in hours 8, 12, 16 respectively. It should be considered that the feeding rate of biomass weight were examined after each took biometrics. Finally, blood samples were taken from the caudal vein of the fish. The results revealed a significant difference between treatments in terms of weight and length (p<0.05) and no significant difference in food intake and growth performance parameters, including FCR, SGR, GR, BWI% and survival rate between treatments (p>0.05). In terms of pigmentation between experimental treatments, astaxanthin was created more change color than control group that using of SalmoFanTM, the degree color of meat in the end of period reach to 28o. Results of blood factors showed that between WBC, RBC, Hb, HCT, Lymphocytes, Neutrophils, Monocytes and IgM were significant differences between treatments (p<0.05). So we can conclude that 41mg/kg astaxanthin dietary, due to economy, would be proper diet in feeding of rainbow trout propagation.