The United States of America, as the main extra-regional actor in the region have had omnipotence in political, strategic and economic equations of the region, so that its political actions have formed the regional power structure. They utilize simultaneously soft and hard power instruments for pursuing their short-term, Mid-term and long-term objectives. The new regional order intended by USA is based on the establishment of balance of power and preventing the emergence of a regional superpower. In other words, USA endeavors to balance, in parallel, the regional powers in the Middle East in order to realize their political, economic and security intentions. In this conjecture, the Islamic Republic of Iran as one of the main powerful regional powers has an important role in the realization of regional order and the formation of political, economic and security structures of the Middle East. Therefore, it seems suitable to reconstruct its strategic policies in conformity with the power structures in the region, taking into account the foreign policies of regional and extra-regional powers, particularly USA, in order to take benefit of the opportunities and to minimize the probable costs. The present article suggests the strategy of “triangular balance of power” and scrutinizes on its requirements especially the adoption of “active neutrality” towards the international powers so that the Islamic Republic of Iran, as the factor of stability in the region, would prevent the vacuum of power in the Middle East.