Introduction: Education and training of the next generation of nurses requires that the curriculum of nursing doctoral programs be in line with the ever-changing global and emerging knowledge sciences. Comparing educational systems can help to enhance academic credibility of educational programs, expand nursing vision, and improve the quality of nursing care. The purpose of this study was to compare the educational system of Nursing Ph. D in Iran and Pennsylvania School of nursing. Methods: This Comparative-analytic study was performed in 2019. The four-stage Beredy model of description, interpretation, neighborhood and comparison was used to compare the nursing educational system in Iran and Pennsylvania School of nursing. Data were collected by Persian and English keywords in Google. Then the data were categorized and compared according to the aim of the research. Results: The structure of nursing Ph. D program in Iran and Pennsylvania are largely similar to each other but there are significant differences in values, philosophy, vision and mission, main goals of the course, admission requirements, curriculum, role dimensions and core competencies of the graduates. These significant differences include international leadership in science, practice and research, global health, diversity of nursing courses tailored to the needs of the community, and interdisciplinary collaboration. Conclusion: According to the findings, PhD in Nursing in Iran, despite the appropriate theoretical content, is weak in terms of clinical dimension and presence in the international arena. Therefore, presenting the doctoral course in clinical nursing, and updating the educational program in accordance with changes in the pattern of diseases, interdisciplinary and international collaboration and paying attention to the role of nursing leadership in science, research and global health is suggested.