Introduction: One of the most serious health threats, which in recent years due to rapid social change, the health organizations, law enforcement and social policy is one of the most important problems in society are taken into consideration, the prevalence of risky behaviors is among adolescents. Therefore, the aim of this study was to investigate the effectiveness of cognitive-social problem-solving skills training on coping strategies and feelings of failure in adolescents with high-risk behaviors. Methods: The research method was quasi-experimental with a pretest-posttest design with a control group. The statistical population of this study included all female adolescents in Babolsar high school in the academic year 2019. A sampling of this research was done in two stages. A: At this stage, 400 students were randomly selected from all students in a single-stage cluster and a questionnaire of high-risk behaviors of Iranian-born adolescents, Mohammadi and Ahmadabadi (2008) was administered to them. B: The people who had the highest score in the Iranian Adolescents' High-Risk Behavior Questionnaires were identified as 85 people. And then the Blings & Moss Coping Strategies Questionnaire (1984); (The method of answering the questionnaire is that the respondents agree or disagree with these items on a 4-choice scale from never (=1) to forever (=4); Hosseini Ghadmagahi et al. Reported the validity of this questionnaire by internal consistency method from 0. 41 to 0. 66) and Gilbert and Allen Feeling of Failure Questionnaire (1998), (Respondents agree or disagree with these statements on a 5-point scale from strongly agree (=5) to strongly disagree (=1); Tarsafi, Kalantar Koucheh and Leicester Cronbach's alpha coefficients were reported to have a failure feeling questionnaire of 0. 93 for women and 0. 93 for men and convergence validity was reported with Beck Depression Inventory (0. 71); Among them, 36 people were selected as the final sample and randomly assigned to the experimental and control groups (each group consisting of 18 people). The experimental group was exposed to cognitive problem-solving skills training for ten one-and-a-half hour sessions and the control group did not receive any treatment. Results: The results showed that social skills training, cognitive problem solving strategies to reduce the physical and emotion-focused, and increase cognitive strategies perceived social support, and problem-solving and reduce internally and external failure was high-risk adolescents (P<0. 001). Conclusions: Teaching cognitive-social problem-solving skills to adolescents with high-risk behaviors increases positive and negative coping strategies, which in turn can improve long-term relationships with peers that ultimately reduce their sense of failure. The result is an increase in their sense of compatibility.