Background and Aim: Breast masses are one of the common complaints among women in the
world. Among these, breast cancer due to its high prevalence is very important. Three main
modalities for the early diagnosis of breast cancer are physical examination, mammography and
Fine Needle Aspiration (FNA). The goal of the present study was to evaluate the accuracy of FNA
in breast lesions diagnosis.
Materials and Methods: In this analytic study, 92 patients with breast mass referred to the surgery
clinic at Zahedan Khatam hospital, were randomly selected. At first FNA and the open biopsy
methods were carried out. Data were collected based on interview, physical examination, FNA and
open biopsy results.
Results: According to FNA results, three cysts (3.3%) were diagnosed that were excluded from the
study because open biopsy was not carried out on them. Among the remained 89 patients, 7 (7.9%)
were inadequate material, 57 (64%) were benign and 25 (28.1%) were malignant. Comparing with
the results of open biopsy, FNA had 8 false negative, however there werent any false positive
results. Therefore, sensitivity of FNA was 75.8%, its specificity was 100%, its PPV was 100%, and
its NPV was 86%, which were very close to other reports. Accuracy of FNA was 88% which was
lower than open biopsy (100%).
Conclusion: On the basis of this study, it is concluded that FNA is a very simple, cost effective,
and reliable method in differentiating malignant lesions of breast from benign ones. When FNA is
positive, it is a particularly suitable substitution for open biopsy. However, when it is negative but
the physical signs are indicative of malignancy, it would be better to repeat FNA or to do open
biopsy to confirm the diagnosis.