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Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Title: 
Author(s): 

Issue Info: 
  • Year: 

    0
  • Volume: 

    9
  • Issue: 

    5 (پی در پی 40)
  • Pages: 

    -
Measures: 
  • Citations: 

    0
  • Views: 

    712
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title: 
Author(s): 

Issue Info: 
  • Year: 

    0
  • Volume: 

    9
  • Issue: 

    5 (پی در پی 40)
  • Pages: 

    -
Measures: 
  • Citations: 

    0
  • Views: 

    1225
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    7-13
Measures: 
  • Citations: 

    0
  • Views: 

    989
  • Downloads: 

    0
Abstract: 

Background and Objectives: Etomoxir and ranolazine have been considered as two new agents with various effects of metabolic pathways to treatment of ischemic heart diseases. In the present study, their effects on ischemia-reperfusion (I/R) induced arrhythmias were studied and compared together in isolated rat heart. Methods: In this experimental study, male Sprague-Dawley rats (270-330g) were anaesthetized by sodium pentobarbital (50mg/kg, ip) then their hearts were immediately isolated and mounted on a non-recirculating langendorff apparatus at constant pressure. The hearts were divided into three groups randomly (n=10 rats in each group) including control, etomoxir treated and ranolazine treated groups. In the control group, the hearts were perfused by a modified Krebs-Henseleite solution at stabilization, 30min regional ischemia and 30min reperfusion while in the test groups; they were perfused by enriched Krebs solution with etomoxir (1mM) or ranolazine (20mM) from 10min before ischemia to end of reperfusion. Arrhythmias events were assessed according to the Lambeth convention.Findings: In the ischemic phase, the number of ventricular ectopic beats (VEBs) in the control group was 667±116 while perfusion of ranolazine and etomoxir reduced it to 33±16 (p<0.001) and 501±165, respectively. The number of ischemic ventricular tachycardia (VT) was also lowered by ranolazine and etomoxir from 280±50 (control) to 0 (p<0.001) and 146±50, respectively. In addition, both agents significantly decreased the incidence of ischemic VT. The number of reperfusion VEBs and VT were lowered by ranolazine (p<0.01 and p<0.001, respectively). Ranolazine also reduced the incidence of total ventricular fibrillation (VF) and the time spent for reversible VF from 63% and 218±69sec (control) to 0% (p<0.05) and 0 sec (p<0.01), respectively. At the same time, etomoxir in a lower level showed significant antiarrhythmic effects. Comparison between the antiarrhythmic effects of the agents did not show statistically significant difference.Conclusion: The results of this study showed protective effects of etomoxir and ranolazine against I/R induced arrhythmias without any significant difference between the agents. It seems that beneficial effect of etomoxir and ranolazine likely is secondary to indirect increasing in glucose oxidation during I/R.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    14-19
Measures: 
  • Citations: 

    0
  • Views: 

    1115
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Gabapentin is an anticonvulsant drug which also possesses antinociceptive effect in wide spectrum kind of pain, like neuropathic pain. However its effectiveness on visceral pain is not elucidated yet. This study was performed to investigate the effect of gabapentin on acetic acid induced visceral pain in mice and also to evaluate probable involvement of Mu opioid and gabaergic receptors on the gabapentin antinociception.METHODS: In this experimental study, adult male mice weighing 30g were divided into thirteen subsequent groups. In control group, animals received normal saline 40 min before intraperitoneal (ip) injections of 0.6% acetic acid (4ml/kg) and then visceral contractions were measured for 90 min. The mice were given gabapentin (25, 50, 100, & 200 mg/kg/i.p.) and then the visceral contractions were measured in the same way as controls. Other groups were given either naloxone as mu opiod antagonist (4mg/kg/i.p.), or the antagonists of GABAa receptors, picrotoxin (0.75, 1& 1.5 mg/kg/i.p.) or bicuculline (0.5, 0.75, 1.5, & 2 mg/kg/i.p.) 10 min prior to the most effective dose of gabapentin. Thereafter visceral contractions were counted similar to control group.FINDINGS: Gabapentin markedly reduced acetic acid induced visceral pain in mice and dose of 50mg/kg of gabapentin was the most effective (p<0.01). Visceral contractions following naloxone administration (4mg/kg/i.p) 10 min prior to gabapentin was not significantly different from gabapentin group. However, picrotoxin and bicuculline antagonized the inhibitory effect of gabapentin on visceral contractions in a dose dependent manner, i.e. the dose of 1.5 mg/kg/ip of picrotoxin or more like as the dose of 2mg/kg/ip of bicuculline increased the mean number of visceral contractions in comparison with gabapentin group which received 50mg/kg/ip (p<0.05). CONCLUSION: The results showed that picrotoxin and bicuculline are able to antagonize the antinociceptive effect of gabapentin on actic acid induced visceral pain in dose dependent manner. It is implicated that the effect of gabapentin on visceral pain may be mediated partly through the GABAa receptors.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    20-26
Measures: 
  • Citations: 

    0
  • Views: 

    2247
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Evaluation of the quality of food proteins have a great importance because of biological and economical impacts. Among existing methods, NPR (net protein ratio), TPD (true protein digestibility) and PER (protein efficiency ratio) have been suggested as appropriate methods to determine the quality of proteins. This study was conducted to compare protein value of cerelac with homemade food (vetch and rice) in rats.METHODS: This experimental study was conducted on 64 male wistar rats, aged 21 days under 8 diets in 8 groups including: cases (cerelac and homemade food), standard (casein+methionine) and basal (protein free), 4 diets in order to determine NPR and PER and cases, standard and basal, 4 diets to study TPD. Period of study for NPR, TPD and PER were 14, 5 and 28 days. FINDINGS: NPR was 4.3±0.4, 4.3±0.9 and 4.2±0.4, TPD was 92.8±4, 87±8 and 81.1±6.1 and PER was 3±0.2, 2.5±0.4 and 2.7±0.6 for standard, cerelac and homemade food groups, respectively. Difference in NPR, TPD and PER between two baby food groups was not significant.CONCLUSION: The results showed that NPR and TPD for homemade food were nearly equal cerelac and PER was higher than cerelac.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    27-31
Measures: 
  • Citations: 

    0
  • Views: 

    879
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Mycotoxins are toxins produced by fungi and aflatoxin is the most important mycotoxins. When animals consume contaminated feed stuff to aflatoxin B1 (AFB1), the toxin is metabolized in the liver and execrated as aflatoxin M1 (AFM1) via milk and it is potentially hazardous for human health. The aim of this study was to find out the aflatoxins M1 in pasteurized milk consumption in Babol.METHODS: This descriptive study was performed on 144 samples of pasteurized milk which collected from the supermarkets of Babol town during winter 2005 to summer 2006. Milk fat was separated from milk via centrifuge and then skimmed milk for aflatoxin M1 (AFM1) contamination was tested by competitive Enzyme Linked Immunosorbent Assay (ELISA). FINDINGS: The aflatoxin M1 (AFM1) contamination mean in January, February, March, July, August and September were 227.85, 229.64, 233.1, 110.4, 120.17 and 112.48 ng/l, respectively. In winter, contamination level in 91.5% of samples was above 200 ng/l while in summer, contamination level in 100% of samples was 101-150 ng/l. AFM1 contamination levels were range 178.8-253.5 ng/l (mean level: 230.2 ng/l) in summer and were range 103.3 -132.7 ng/l (mean level: 114.35 ng/l) in winter. CONCLUSION: Aflatoxin M1 contamination in pasteurized milk was 100% which was above than recommended limit of European community regulations (50 ng/l) and it is a serious problem for public health, and is potentially hazardous for human health. To minimize aflatoxin M1 contamination in milk, animal feedstuff should be evaluated for aflatoxin and feedstuff should be kept away from probable contamination.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    32-36
Measures: 
  • Citations: 

    0
  • Views: 

    4354
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Hyperbilirubinemia is one of the most common causes of readmission to hospital in newborns. Early diagnosis of hyperbilirubinemia can decrease its complications. The aim of this study was to determine the relationship between umbilical cord bilirubin with maternal blood group.METHODS: This cross sectional study was done on 290 full term newborns at Babolclinic hospital in Babol town. Two milliliter clotted and citrated blood sample were drawn from umbilical cord after clamping the cord of all neonates for determining blood group, Rh and bilirubin level. FINDINGS: Of 290 cases, 21 were excluded from this study because their mothers’ files were incomplete. From 269 cases, 103 (38.3%), 77 (28.6%), 71 (26.4%) and 18 (6.7%) cases were with blood groups O, B, A and AB, respectively. Also 240 (89.2%) cases were RH+ and 29 (10.8%) were RH-. The mean of total bilirubin in neonates of mothers with RH+ and RH- was 1.88±0.47 and 1.75±0.35, respectively (p=0.14). Maximum bilirubin level was observed in subjects with blood group O (1.93±0.45) that compared to other blood groups and there was not a significant difference. But mean of direct bilirubin level in different blood groups was significant (p=0.04).CONCLUSION: The result showed that umbilical cord bilirubin in neonates of mother with blood group O was higher than other blood groups. Based on this finding, follow up of newborns of mother with blood group O is precisely recommended after discharge.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    37-40
Measures: 
  • Citations: 

    0
  • Views: 

    1883
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Treatment of nasolacrimal obstruction is controversial. The purpose of this study was to compare the efficacy of dacryocystorhinostomy (DCR) with catheter intubation or bodkin tube in the treatment of nasolacrimal obstruction.METHODS: This Quasi- experimental study was conducted on patients with lacrimal obstruction who referred to the department of ophthalmology, Babol Medical University from 1999 to 2006. All cases were treated with DCR with intubation or Bodkin tube. Catheter or bodkin tube was drawn out 3 weeks and 4 months, respectively. After treatment all cases were followed at a 3 month interval for one year. Success rates in these two treated groups were compared. FINDINGS: In group DCR with catheter, 79 cases (50 females, 29 males) with the mean age of 34±16 years and in group bodkin tube, 103 cases (50 females, 53 males) with the mean age of 35±0.5 years were treated. The mean age and sex distribution among these two treated groups were equal (p=0.052). The success rate with DCR with catheter intubation was 96.2% and DCR with Bodkin tube was 99.1%. Significant difference was not seen between two groups in treatment failure.CONCLUSION: Dacryocystorhinostomy with catheter intubation or bodkin tube both have the same efficacy for treatment of nasolacrimal obstruction. However the efficacy of dacryocystorhinostomy with Bodkin tube is associated with lower recurrence rate but the difference was not significant.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    41-44
Measures: 
  • Citations: 

    0
  • Views: 

    716
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Endodontic implants are metalic extension of a tooth root using a post prepared for maintaining teeth that must be extracted. One of the most important factors of implant failures is improper apical seal between implant and end of root. The purpose of this study was to evaluate the effect of MTA (mineral trioxide aggregate) on apical seal surround endodontic implants.METHODS: In this experimental in-vitro study twenty eight freshly extracted human maxillary central incisors and canines were used. After cleaning, all teeth were cast in putty and then removed from cast and cut from middle one third of the root. Access cavity was made and canals enlarged with hand instrumentation and piezoreamer drills in such manner that drills were extruded from apex. The teeth were replaced in the cast and buccal portion of the cast was removed. Teeth were randomly divided into two groups. In group A implants were placed at canals through access cavity and cement with glass ionomer cement. In group B before implant placement, MTA packed at the end of the canals then a tract were made within them. After MTA setting, implants were placed at the canals like group A and cemented with glass ionomer cement. Access cavity sealed and all surfaces of the teeth were covered with two layer of nail varnish except apical 2 millimeters. Dye penetration was measured using foshin solution. After splitting the teeth longitudinally, dye penetration was measured by stereomicroscope.FINDINGS: Average of dye penetration for group A and B is 0.32 and 0.22mm, respectively. The average of dye penetration in group A was significantly higher than group B (p<0.05).CONCLUSION: Application of MTA improves apical seal surround endodontic implants, thus increase successful rate of it.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    45-49
Measures: 
  • Citations: 

    1
  • Views: 

    3577
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: One of the problems that the developed societies are faced to it is smoking. The oral mucosa and the tongue are also exposed to the tobacco products and smoke. Coated and hairy tongue is the lesions that can be developed due to the use of tobacco. The aim of this study was to determine the influence of the amount of cigarette smoking on the occurrence of two lesions called coated and hairy tongue.METHODS: This cross sectional study was done on 534 subjects (262 non-smokers, 136 smokers and 136 heavy smokers) of the male patients who were referred to the oral disease section of Babol dental school during 2005 and 2006. Patients who didn't receive antibiotic, oxidizing mouthwashes, antiacids, alcohol and coffee during the past month and didn't have removable prosthesis and the history of systemic disease were included in the study. The patients have been matched in three groups according to the amount of cigarette consumption.FINDINGS: The frequency of coated tongue in the three groups non-smokers, smokers and heavy smokers were 26 (9.9%), 50 (36.8%) and 70 (51.5%), respectively and also the frequency of hairy tongue were 1 (0.4%), 5 (3.7%), 32 (23.5%), respectively. Furthermore, the frequency of coated tongue and hairy tongue in heavy smokers was significantly higher than smokers (p=0.01, p<0.0001, respectively) and in smokers was significantly higher than non-smokers (p<0.0001).CONCLUSION: The results of this study indicate that the quality of cigarette smoking has a positive correlation with the probability of occurrence of coated tongue and hairy tongue.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    50-54
Measures: 
  • Citations: 

    0
  • Views: 

    1231
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Mother’s nutrition affects pregnancy outcome. Variety and balance in diet of mother and using the five food groups are important during pregnancy. Overfeeding and underfeeding should be avoided by mothers. The aim of this study was to determine the nutritional knowledge of pregnant women referred to health and therapeutic centers of Babol.METHODS: This cross sectional study was performed on 247 pregnant women referred to health and therapeutic centers of Babol. Two standard questionnaires included nutritional knowledge and general characteristics of mother were completed for every woman. Nutritional knowledge of pregnant women was evaluated by good score (50-70), moderate score (29-49) and poor score (20-28).FINDINGS: Totally, level of nutritional knowledge of pregnant women (65.6%) was moderate. The most important information focal points of pregnant women about nutrition were health care workers (32%) and also radio and television (29.6%). A significant correlation was not found between knowledge level of pregnant women and their mean age (r=0.117). Also a significant relationship was not observed between monthly income, gravidity and familial dimension with their nutritional knowledge. The relationship between nutritional knowledge level with educational level of women was significant (p=0.002).CONCLUSION: The results showed that the information level of pregnant women was moderate. So the promotion of nutritional knowledge of pregnant women by personnel of health center and the mass media is necessary.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    55-60
Measures: 
  • Citations: 

    3
  • Views: 

    1939
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Diabetes is a chronic disease that quality of life is one of the very important concepts in this disease. In general quality of life has five aspects including physical, psychological, social, somatic, and spiritual. Since short and long time complications of this disease need to very costs, so the goal of this study was to determine the quality of life of these patients compared with non diabetic people.METHODS: This is a cross sectional study in which a total of 70 patients with type 2 diabetes and 75 non diabetic accompaniers of them were included. This study was performed at Shahid Rajaei hospital in Tonekabon, and Emam Sajjad hospital in Ramsar, IRAN. A questionnaire composed of Persian translations of SF_36 and Sweden QOL (quality of life) questionnaires were used for measuring of HRQL (health related quality of life) after determining its validity and reliability. The questionnaire including demographic data and seven dimensions: physical function, pain, daily activities, feeling, sleep, relation with relatives, and overall health. FINDINGS: The mean and standard deviation (SD) of QOL associated to diabetic patients and non diabetic people was (131.72±25.88) and (97.75±23.8), respectively that demonstrates adverse QOL in diabetic patients, and good QOL in non diabetic people. There was a statistically significant relationship between demographic variable such as age, sex, and quality of life in diabetic and non diabetic groups.CONCLUSION: Since type 2 diabetes cause many changes in QOL, so treatment strategies should be considered to solve this problem.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    9
  • Issue: 

    5 (40)
  • Pages: 

    61-64
Measures: 
  • Citations: 

    0
  • Views: 

    1833
  • Downloads: 

    0
Abstract: 

BACKGROUND AND OBJECTIVES: Malignant infantile osteopetrosis is a rare congenital disorder due to defect in osteoclastic activity and bone marrow disappearance and causes severe complications and mortality, while on time treatment can improve this situation.CASE: The patient was a 55 day old boy who was admitted with chief complaints of abdominal distension, fever and poor feeding and while he had hepatosplenomegaly, anemia, thrombocytopenia and femur fracture, with impression of sepsis, treatment was begun for him, and after relative improvement referred to hematology ward for definite diagnosis and after improvement of malignant infantile osteopetrosis disease, bone marrow transplantation was advised for him.CONCLUSION: Neonates and infants with sepsis, hepatosplenomegaly and bone marrow failure must be considered for this disease to prevent multiple fractures and delay of definite treatment.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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