This research was conducted to study the effects of water deficiency stress, nitrogen application rates, and plant population on kernel and dry matter yields, nitrogen agronomic efficiency, nitrogen use efficiency and nitrogen recovery fraction of grain com (hybrid SC.704) in 2003 in experimental field in Natural Resources and Agricultural Sciences University of Khuzestan, Ahvaz. This study was consisted of three separate split-plot experiments, using. Randomized Complete Block Design (RCBD). In each experiment, one of the following irrigation treatments was implemented; optimum irrigation, moderate stress and severe drought stress where irrigation was done after depletion of 30%, 40% and 50% of field capacity, respectively. Irrigation treatments implement at 4-5 leaf stage (seedling establishment) and continued until 10 days before physiological maturity. In each experiment three nitrogen lease consisting of 140, 180, and 220 Kg N ha-1 were considered as main plots and subplots consisted of three plant population of 6, 7.5, and 9 plant m-2. There were three replications in each experiment. The results of combined analysis indicated that the effect of drought stress, nitrogen and plant population on kernel and dry matter yields, leaf area index and relative water content was significant. The increase of drought stress severity caused significant decrease in kernel and dry matter yields, leaf area index and relative water content. Severe drought stress reduced the kernel yield by 40% compared to the optimum irrigation condition. This reduction was mainly due to reduction in kernel number per ear and kernel weight. Kernel and dry matter yields increased with nitrogen application rate. The response of kernel and dry matter yields to increase in plant population was positive. Increase in drought stress severity and nitrogen application rate, caused significant decrease in nitrogen agronomic efficiency, nitrogen use efficiency and nitrogen recovery fraction. The response of these efficiencies to plant population was positive. Results of this study indicated that nitrogen application rate and plant population should be adjusted accordingly with the availability of water in the soil to obtain highest input use efficiency and therefore, minimizing production costs.