Collagenous Enteritis-An Alternative Cause of Malabsorptive Enteropathy

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Mirakhor Ebrahim; Choe June; Goodman Robert I.

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF COLORECTAL RESEARCH Year:2021 | Volume:9 | Issue:2 Page(s): 78-81

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Information Journal Paper

Title

Collagenous Enteritis-An Alternative Cause of Malabsorptive Enteropathy

Author(s)

Mirakhor Ebrahim | Choe June | Goodman Robert I. | Issue Writer Certificate

Keywords

Collagenous sprue

Malabsorption

Diarrhea

Abstract

Introduction: Collagenous Enteritis (CE) is a recently described and rare pathological diagnosis characterized by intestinal villus blunting, intraepithelial lymphocytic infiltrate, and expanded subepithelial collagenous bands. Case Presentation: We discuss the case of a 40-year-old woman with prior history of cervical cancer who presented to our center with a two-year history of progressive unintentional weight loss (32 kg), chronic diarrhea, and severe malnutrition. During this time, she was labeled as having celiac disease but despite documented adherence to a prolonged gluten-free diet, she continued to experience diarrhea, fatigue, and weight loss. After extensive workup, pathology from a follow-up push enteroscopy revealed the presence of intestinal intraepithelial lymphocytosis and severe villus blunting in addition to a patchy enlarged subepithelial collagen layer characteristic of CE extending from the duodenum to the terminal ileum. Conclusion: With a better understanding of CE and its response to various treatment modalities, a more favorable outlook has replaced its once grim prognosis. Discontinuation of offending medications and initiation of corticosteroids remain the mainstay of therapy, often with favorable outcomes. In our case, treatment with corticosteroids and maintenance on a strict gluten-free diet resulted in significantly reduced stool output and gradual weight gain.

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APA: Copy

Mirakhor, Ebrahim, Choe, June, & Goodman, Robert I.. (2021). Collagenous Enteritis-An Alternative Cause of Malabsorptive Enteropathy. IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH), 9(2), 78-81. SID. https://sid.ir/paper/1002801/en

Vancouver: Copy

Mirakhor Ebrahim, Choe June, Goodman Robert I.. Collagenous Enteritis-An Alternative Cause of Malabsorptive Enteropathy. IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH)[Internet]. 2021;9(2):78-81. Available from: https://sid.ir/paper/1002801/en

IEEE: Copy

Ebrahim Mirakhor, June Choe, and Robert I. Goodman, “Collagenous Enteritis-An Alternative Cause of Malabsorptive Enteropathy,” IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH), vol. 9, no. 2, pp. 78–81, 2021, [Online]. Available: https://sid.ir/paper/1002801/en

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