Liver Fibrosis Assessment Using Transient Elastography by FibroScan and ShearWave Elastography by Sonography: A Comparative Cross-sectional Study in an Outpatient Liver Clinic

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Zarei Fariba; MOINI MARYAM; Abedi Mahsa; Ravanfar Haghighi Rezvan; ZEINALI RAFSANJANI BANAFSHEH

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Journal: IRANIAN JOURNAL OF RADIOLOGY Year:2021 | Volume:18 | Issue:AB0040 Page(s): 0-0

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Title

Liver Fibrosis Assessment Using Transient Elastography by FibroScan and ShearWave Elastography by Sonography: A Comparative Cross-sectional Study in an Outpatient Liver Clinic

Author(s)

Keywords

Liver Fibrosis

Fibroscan

ShearWave

Transient Elastography

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is the second most common cause of liver transplantation in the United States, with a continuously growing prevalence. There are several non-invasive methods to detect liver fibrosis, which is defined as the accumulation of extracellular matrix proteins, particularly collagens. It is most commonly associated with chronic liver diseases, such as NAFLD. Objectives: This study aimed to investigate the concordance between transient elastography (TE) and shear wave elastography (SWE) for liver fibrosis staging and also to examine the congruence between the controlled attenuation parameter (CAP) and the B-mode hepatorenal ratio for hepatic steatosis grading in patients with NAFLD. Patients and Methods: In this cross-sectional study conducted during March 2018-2019, NAFLD patients, referred to the liver clinic of our center for the non-invasive assessment of hepatic fibrosis, were enrolled. However, patients with sonographic features of cirrhosis, multiple hepatic masses, or moderate to large ascites were excluded,also, patients who were uncooperative during the tests were excluded. Measurements obtained by different tools were recorded. Kolmogorov-Smirnov test, Chi-square test, independent t-test, or Mann-Whitney tests, as well as Pearson’, s correlation coefficient test, were used to analyze the data. Results: Sixty-five patients (male-to-female ratio, 1: 13), with a median age of 47 years, were included in the study. The tools for assessing fibrosis (r = 0. 9538, 95% CI: 0. 9252-0. 9717, P < 0. 0001) and steatosis (r = 0. 429, 95% CI: 0. 2048-0. 6104, P < 0. 0001) were perfectly and moderately correlated, respectively. Sex, age, and body mass index (BMI) did not affect the results. Conclusion: The two elastography modalities showed a strong correlation for fibrosis staging in our study population. Also, the CAP and B-mode hepatorenal ratio were moderately correlated for grading hepatosteatosis. Overall, selection of the best assessment method among the studied modalities depends on factors other than internal validity.

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APA: Copy

Zarei, Fariba, MOINI, MARYAM, Abedi, Mahsa, Ravanfar Haghighi, Rezvan, & ZEINALI RAFSANJANI, BANAFSHEH. (2021). Liver Fibrosis Assessment Using Transient Elastography by FibroScan and ShearWave Elastography by Sonography: A Comparative Cross-sectional Study in an Outpatient Liver Clinic. IRANIAN JOURNAL OF RADIOLOGY, 18(4), 0-0. SID. https://sid.ir/paper/1036132/en

Vancouver: Copy

Zarei Fariba, MOINI MARYAM, Abedi Mahsa, Ravanfar Haghighi Rezvan, ZEINALI RAFSANJANI BANAFSHEH. Liver Fibrosis Assessment Using Transient Elastography by FibroScan and ShearWave Elastography by Sonography: A Comparative Cross-sectional Study in an Outpatient Liver Clinic. IRANIAN JOURNAL OF RADIOLOGY[Internet]. 2021;18(4):0-0. Available from: https://sid.ir/paper/1036132/en

IEEE: Copy

Fariba Zarei, MARYAM MOINI, Mahsa Abedi, Rezvan Ravanfar Haghighi, and BANAFSHEH ZEINALI RAFSANJANI, “Liver Fibrosis Assessment Using Transient Elastography by FibroScan and ShearWave Elastography by Sonography: A Comparative Cross-sectional Study in an Outpatient Liver Clinic,” IRANIAN JOURNAL OF RADIOLOGY, vol. 18, no. 4, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/1036132/en

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