EVALUATION OF PENTOXIFYLLINE EFFECT IN TREATMENT OF ANKYLOSIS SPONDYLITIS PATIENTS REFERRED TO RASOOL-E-AKRAM HOSPITAL

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SHIRANI FATEMEH; SEBT ROZATI SEYED MEHDI

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Journal: Razi Journal of Medical Sciences Year:2011 | Volume:18 | Issue:87 Page(s): 8-13

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Title

EVALUATION OF PENTOXIFYLLINE EFFECT IN TREATMENT OF ANKYLOSIS SPONDYLITIS PATIENTS REFERRED TO RASOOL-E-AKRAM HOSPITAL

Author(s)

SHIRANI FATEMEH | SEBT ROZATI SEYED MEHDI | Issue Writer Certificate

Keywords

ANALYZING SPONDYLITISQ2

BASDAI (BATH ANKYLOSING SPONDYLITIS DISEASE ACTIVITY INDEX)Q2

PENTOXIFYLLINEQ2

Abstract

Background: Ankylosing spondylitis (AS) is a spondyloarthropathy of unknown etiology, with widespread effect on axial and peripheral skeleton. The aim of this study was determination of PENTOXIFYLLINE effect on Bath Ankylosing spondylitis Disease Activity Index (BASDAI) of uncontrolled AS patients in Rasool-e-Akram Hospital Rheumatology Clinic.Methods: This pilot study was performed on 30 patients with ankylosis spondylitis with BASDAI³4 ignoring their previous medical treatments. The patients received PENTOXIFYLLINE tablets 400 mg TDS and then evaluated 6 and 12 weeks after the treatment. Data were analyzed by Paired T test and p<0.05 was considered to be significant.Results: 30 patients (26 males (86.7%), 4 females (13.3%)) with ankylosing spondylitis were evaluated. Mean age of patients was 32.42±8.14. Mean±standard deviation of BASDAI was 6.53±1.72 prior to the treatment, which decreased to 5.17±1.58 after 6 weeks and 4.88±1.66 after 12 weeks of treatment (p=0.000). The differences of BASDAI before and after treatment with PENTOXIFYLLINE were significant.Conclusion: PENTOXIFYLLINE can be advised for uncontrolled AS patients regardless of current or previous treatment.

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APA: Copy

SHIRANI, FATEMEH, & SEBT ROZATI, SEYED MEHDI. (2011). EVALUATION OF PENTOXIFYLLINE EFFECT IN TREATMENT OF ANKYLOSIS SPONDYLITIS PATIENTS REFERRED TO RASOOL-E-AKRAM HOSPITAL. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 18(87), 8-13. SID. https://sid.ir/paper/10495/en

Vancouver: Copy

SHIRANI FATEMEH, SEBT ROZATI SEYED MEHDI. EVALUATION OF PENTOXIFYLLINE EFFECT IN TREATMENT OF ANKYLOSIS SPONDYLITIS PATIENTS REFERRED TO RASOOL-E-AKRAM HOSPITAL. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2011;18(87):8-13. Available from: https://sid.ir/paper/10495/en

IEEE: Copy

FATEMEH SHIRANI, and SEYED MEHDI SEBT ROZATI, “EVALUATION OF PENTOXIFYLLINE EFFECT IN TREATMENT OF ANKYLOSIS SPONDYLITIS PATIENTS REFERRED TO RASOOL-E-AKRAM HOSPITAL,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 18, no. 87, pp. 8–13, 2011, [Online]. Available: https://sid.ir/paper/10495/en

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