THE EFFECT OF AEROBIC EXERCISE WITH MELATONIN CONSUMPTION ON THE EXPRESSION OF HSP60 AND HSP70 MARKERS IN RAT MYOCARD AFTER ISCHEMIC-REPERFUSION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JOKAR MASOUD; MOTAMEDI PEZHMAN; NABIUNI MOHAMMAD; RAJABI HAMID; KHALEDI NEDA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Knowledge & Health in Basic Medical Sciences Year:2017 | Volume:12 | Issue:1 Page(s): 73-80

Download Full-Text

Persian Verion

View:

907

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF AEROBIC EXERCISE WITH MELATONIN CONSUMPTION ON THE EXPRESSION OF HSP60 AND HSP70 MARKERS IN RAT MYOCARD AFTER ISCHEMIC-REPERFUSION

Author(s)

Keywords

APOPTOSISQ2

AEROBIC EXERCISEQ2

MELATONINQ2

HSP60Q2

HSP70Q2

Abstract

Full Text [PDF 915KB] Introduction: The aim of study was to examine the effect of AEROBIC EXERCISE with MELATONIN consumption on the expression of HSP60 and HSP70 markers in rat myocard after ischemic-reperfusion by isoprenaline.Methods: 30 male Wistar rats were used weighing approximately 200-250 g with two to three months old. Then the rats divided into five groups: pilot (n=4), control (n=4), MELATONIN (n=4), aerobic (n=4) and MELATONIN aerobic (n=4). Rats in MELATONIN group were gavaged every day for one month using a dose of 10 mg/kg BW. Meanwhile, rats in aerobic group and MELATONIN aerobic group were familiar with running on treadmill for one week, and then they were exposed training course with frequency of three times weekly for one month. After one month, all rats were injected isoprenaline with dose of 150 and 125 mg/kg BW with 24 hours in two consecutive days. Finally, rats were sacrificed after confirmation of infarct and expression of HSP60 and HSP70 gene were studied by real-time method. Data were analyzed with 2-DDct formula, one-way ANNOVA and Kruskal Wallis methods.Results: The results showed that there are significant differences in HSP70 gene expression between different groups (P£0.05) but there aren’t significant differences in HSP70 gene expression between MELATONIN and MELATONIN aerobic groups (P³0.669). Also there aren’t significant differences in HSP60 gene expression between different groups (P³0.05).Conclusion: MELATONIN treatment and aerobic training have negligible effect on HSP60 and HSP70 gene expression. In the other hand, AEROBIC EXERCISE with consuming MELATONIN can decrease and increase HSP60 and HSP70 gene expression respectively.

Cites

No record.

References

No record.

Cite

APA: Copy

JOKAR, MASOUD, MOTAMEDI, PEZHMAN, NABIUNI, MOHAMMAD, RAJABI, HAMID, & KHALEDI, NEDA. (2017). THE EFFECT OF AEROBIC EXERCISE WITH MELATONIN CONSUMPTION ON THE EXPRESSION OF HSP60 AND HSP70 MARKERS IN RAT MYOCARD AFTER ISCHEMIC-REPERFUSION. KNOWLEDGE AND HEALTH, 12(1 ), 73-80. SID. https://sid.ir/paper/107887/en

Vancouver: Copy

JOKAR MASOUD, MOTAMEDI PEZHMAN, NABIUNI MOHAMMAD, RAJABI HAMID, KHALEDI NEDA. THE EFFECT OF AEROBIC EXERCISE WITH MELATONIN CONSUMPTION ON THE EXPRESSION OF HSP60 AND HSP70 MARKERS IN RAT MYOCARD AFTER ISCHEMIC-REPERFUSION. KNOWLEDGE AND HEALTH[Internet]. 2017;12(1 ):73-80. Available from: https://sid.ir/paper/107887/en

IEEE: Copy

MASOUD JOKAR, PEZHMAN MOTAMEDI, MOHAMMAD NABIUNI, HAMID RAJABI, and NEDA KHALEDI, “THE EFFECT OF AEROBIC EXERCISE WITH MELATONIN CONSUMPTION ON THE EXPRESSION OF HSP60 AND HSP70 MARKERS IN RAT MYOCARD AFTER ISCHEMIC-REPERFUSION,” KNOWLEDGE AND HEALTH, vol. 12, no. 1 , pp. 73–80, 2017, [Online]. Available: https://sid.ir/paper/107887/en

Related Journal Papers