Evaluation of Melatonin on HSP60 and HSP70 Gene Expression Following High-Intensity Anaerobic Training after Ischemia-Reperfusion in Male Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JOKAR MASOUD; Motamedi Pejman

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Scientific Medical Journal Year:2019 | Volume:18 | Issue:5 Page(s): 471-484

Download Full-Text

Persian Verion

View:

377

Download:

Cites:

Information Journal Paper

Title

Evaluation of Melatonin on HSP60 and HSP70 Gene Expression Following High-Intensity Anaerobic Training after Ischemia-Reperfusion in Male Rats

Author(s)

JOKAR MASOUD | Motamedi Pejman | Issue Writer Certificate

Keywords

MelatoninQ2

HSP70Q1

HSP60Q1

Anaerobic TrainingQ1

Ischemia-ReperfusionQ1

Abstract

Background and Objective: The aim of the present study was to evaluate the effect of Melatonin supplementation on HSP60 and HSP70 gene expression changes following high intensity anaerobic exercise in male rats after Ischemia-Reperfusion. Materials and Methods: Twenty four male Wistar rats weighing approximately 200-250g were divided into 4 groups of 6 each: study groups including control, Melatonin, Anaerobic Training, and anaerobic+Melatonin training. The anaerobic exercise protocol was performed for one month, while the Melatonin Anaerobic Training group underwent Melatonin gavage during the exercise. At the end of one month, rats were injected with isoprenaline after two days of rest to induce Ischemia-Reperfusion. After two days the rats were killed, their left ventricle removed and the expression levels of HSP60 and HSP70 genes were measured by RNA extraction and Real Time technique. Results: Results showed that Melatonin consumption decreased HSP60 and increased HSP70 apoptotic gene expression after anaerobic exercise (P <0. 05). Conclusion: The results of this study showed that intake of Melatonin concurrent with intensive anaerobic exercise reduce the volume of myocardial apoptosis after Ischemia-Reperfusion-induced Ischemia-Reperfusion.

Cites

No record.

References

No record.

Cite

APA: Copy

JOKAR, MASOUD, & Motamedi, Pejman. (2019). Evaluation of Melatonin on HSP60 and HSP70 Gene Expression Following High-Intensity Anaerobic Training after Ischemia-Reperfusion in Male Rats. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 18(5 ), 471-484. SID. https://sid.ir/paper/366017/en

Vancouver: Copy

JOKAR MASOUD, Motamedi Pejman. Evaluation of Melatonin on HSP60 and HSP70 Gene Expression Following High-Intensity Anaerobic Training after Ischemia-Reperfusion in Male Rats. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2019;18(5 ):471-484. Available from: https://sid.ir/paper/366017/en

IEEE: Copy

MASOUD JOKAR, and Pejman Motamedi, “Evaluation of Melatonin on HSP60 and HSP70 Gene Expression Following High-Intensity Anaerobic Training after Ischemia-Reperfusion in Male Rats,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 18, no. 5 , pp. 471–484, 2019, [Online]. Available: https://sid.ir/paper/366017/en

Related Journal Papers