Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide

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Rahimy Milad; AZARBAYJANI MOHAMMAD ALI; PEERI MAGHSOUD; FARZANEGI PARVIN

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Journal: Razi Journal of Medical Sciences Year:2020 | Volume:26 | Issue:12 Page(s): 149-155

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Title

Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide

Author(s)

Rahimy Milad | AZARBAYJANI MOHAMMAD ALI | PEERI MAGHSOUD | FARZANEGI PARVIN | Issue Writer Certificate

Keywords

Aerobic trainingQ1

Oxidative StressQ2

HSP70Q1

Abstract

Background: The purpose of present study was to investigate the effect of Aerobic training and vitamin D on the gene expression of HSP70 in the lung tissue of rats exposed to oxygenated water. Methods: In this experimental study, 30 male male Wistar rats were randomly divided into five groups of six each: oxygenated water, oxygenated water plus vitamin D, oxygenated water plus Aerobic training, and oxygenated water plus Aerobic training plus vitamin D. The groups underwent the respective interventions for 8 weeks. HSP70 gene expression were measured by real time and PCR. Results: The Aerobic training and vitamin D a lonely caused significant decrease in gene expression of HSP70 compared to oxygenated water (P<0. 05) but the interaction effect of Aerobic training and vitamin D interactiondid not significant. Conclusion: It seems that Aerobic training and vitamin D induce improve of Oxidative Stress and inflammation in lung tissue.

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APA: Copy

Rahimy, Milad, AZARBAYJANI, MOHAMMAD ALI, PEERI, MAGHSOUD, & FARZANEGI, PARVIN. (2020). Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 26(12 ), 149-155. SID. https://sid.ir/paper/364587/en

Vancouver: Copy

Rahimy Milad, AZARBAYJANI MOHAMMAD ALI, PEERI MAGHSOUD, FARZANEGI PARVIN. Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2020;26(12 ):149-155. Available from: https://sid.ir/paper/364587/en

IEEE: Copy

Milad Rahimy, MOHAMMAD ALI AZARBAYJANI, MAGHSOUD PEERI, and PARVIN FARZANEGI, “Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 26, no. 12 , pp. 149–155, 2020, [Online]. Available: https://sid.ir/paper/364587/en

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