Antifungal Resistance of Clinical Candida albicans Isolates in Iran: A Systematic Review and Meta-Analysis

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Kermani Firoozeh; TAGHIZADEH ARMAKI MOJTABA; Hosseini Seyed Abdollah; AMIRRAJAB NASRIN; Javidnia Javad; FAMI ZAGHRAMI MAHMOUD; SHOKOHI TAHEREH

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Journal: Iranian Journal of Public Health Year:2023 | Volume:52 | Issue:2 Page(s): 290-305

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Title

Antifungal Resistance of Clinical Candida albicans Isolates in Iran: A Systematic Review and Meta-Analysis

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Keywords

Antifungal susceptibility

Multi-drug resistance

Candida albicans

Systematic review

Abstract

Background: The present Systematic review aimed to investigate the drug susceptibility patterns of Iranian clinical Candida albicans isolates to antifungal drugs (azoles, polyenes, and echinocandins). Methods: Six electronic databases including “, PubMed, ”,“, Scopus, ”,“, Web of Science, ”,“, IranDoc”, , “, SID”, , and “, Magiran”,were searched from May 2000 to June 2021. The susceptibility of 6322 C. albicans strains from 19967 patients against 14 antifungal drugs was evaluated according to CLSI method. Results: The pooled prevalence of antifungal resistance ranged from 0% to 26%. The lowest resistance levels among azoles were observed in luliconazole with a frequency of 0% and voriconazole of 3. 94%. Conclusion: Due to the emergence of multi-drug resistant C. albicans, rational drug prescription based on the anti-fungal stewardship strategy and therapeutic drug monitoring is warranted.

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APA: Copy

Kermani, Firoozeh, TAGHIZADEH ARMAKI, MOJTABA, Hosseini, Seyed Abdollah, AMIRRAJAB, NASRIN, Javidnia, Javad, FAMI ZAGHRAMI, MAHMOUD, & SHOKOHI, TAHEREH. (2023). Antifungal Resistance of Clinical Candida albicans Isolates in Iran: A Systematic Review and Meta-Analysis. IRANIAN JOURNAL OF PUBLIC HEALTH, 52(2), 290-305. SID. https://sid.ir/paper/1099378/en

Vancouver: Copy

Kermani Firoozeh, TAGHIZADEH ARMAKI MOJTABA, Hosseini Seyed Abdollah, AMIRRAJAB NASRIN, Javidnia Javad, FAMI ZAGHRAMI MAHMOUD, SHOKOHI TAHEREH. Antifungal Resistance of Clinical Candida albicans Isolates in Iran: A Systematic Review and Meta-Analysis. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2023;52(2):290-305. Available from: https://sid.ir/paper/1099378/en

IEEE: Copy

Firoozeh Kermani, MOJTABA TAGHIZADEH ARMAKI, Seyed Abdollah Hosseini, NASRIN AMIRRAJAB, Javad Javidnia, MAHMOUD FAMI ZAGHRAMI, and TAHEREH SHOKOHI, “Antifungal Resistance of Clinical Candida albicans Isolates in Iran: A Systematic Review and Meta-Analysis,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 52, no. 2, pp. 290–305, 2023, [Online]. Available: https://sid.ir/paper/1099378/en

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