THE ROLE OF HER- 2 IN PROGNOSIS AND TREATMENT OF BREAST CANCER ARTICLE REVIEW

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MIRMALEK S.A.; ELHAMKANI E.; MAHMOUDZADEH H.

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Journal: Iranian Journal of Surgery Year:2005 | Volume:13 | Issue:2 (35) Page(s): 7-21

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Title

THE ROLE OF HER- 2 IN PROGNOSIS AND TREATMENT OF BREAST CANCER ARTICLE REVIEW

Author(s)

MIRMALEK S.A. | ELHAMKANI E. | MAHMOUDZADEH H. | Issue Writer Certificate

Keywords

BREAST CARCINOMAQ3

HER-2Q4

Abstract

Introduction & Objective: Human Epidermal growth factor Receptor-2 as a new prognostic and predictive factor has been believed as an essential measurement in BREAST CARCINOMA.Materials & Methods: Review of recent published articles on HER-2, selecting 280 and referring to 115 articles.Results: Human Epidermal growth factor Receptor-2 is an oncoprotein epidermal growth factor receptor produced by a so called cell surface oncogene. Overexpression results in aggressive behavior; early lymphnode and distant metastasis and poor prognosis in BREAST CARCINOMA.Positive HER-2 as a Predictive factor leads to a biologic and less side results treatment (Herceptin).Conclusions: HER-2 is a prognostic and Predictive factor and must be considered in all BREAST CARCINOMA cases.

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APA: Copy

MIRMALEK, S.A., ELHAMKANI, E., & MAHMOUDZADEH, H.. (2005). THE ROLE OF HER- 2 IN PROGNOSIS AND TREATMENT OF BREAST CANCER ARTICLE REVIEW. IRANIAN JOURNAL OF SURGERY, 13(2 (35)), 7-21. SID. https://sid.ir/paper/112886/en

Vancouver: Copy

MIRMALEK S.A., ELHAMKANI E., MAHMOUDZADEH H.. THE ROLE OF HER- 2 IN PROGNOSIS AND TREATMENT OF BREAST CANCER ARTICLE REVIEW. IRANIAN JOURNAL OF SURGERY[Internet]. 2005;13(2 (35)):7-21. Available from: https://sid.ir/paper/112886/en

IEEE: Copy

S.A. MIRMALEK, E. ELHAMKANI, and H. MAHMOUDZADEH, “THE ROLE OF HER- 2 IN PROGNOSIS AND TREATMENT OF BREAST CANCER ARTICLE REVIEW,” IRANIAN JOURNAL OF SURGERY, vol. 13, no. 2 (35), pp. 7–21, 2005, [Online]. Available: https://sid.ir/paper/112886/en

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