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Information Journal Paper

Title

ANTIMICROBIAL EFFECT OF ETHANOLIC EXTRACT OF CALENDUAL OFFICINALIS L. AGAINSTOF STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS, ESCHERICHIA COLI ANDPSEUDOMONAS AERUGINOSA SSTRAINS IN VITRO

Pages

  61-69

Abstract

 Background and Aim: Nowadays, the increasing spread of drug resistance among bacteriahas led to the use of other methods including herbal medicines to control human infectionsworldwide. This study was conducted to determine the ANTIBACTERIAL EFFECTs of ethanolicextract of flowering plants CALENDUAL OFFICINALIS L. against some pathogen microorganisms. Material and Method: The studied plant was collected from Marand city in East Azerbaijan, Iran and were confirmed as CALENDUAL OFFICINALIS L. by botanists of East research center. ETHANOLIC EXTRACT of flowers was prepared in different concentrations (0/19, 0/39, 0/75, 1/56, 3/12, 6/25, 12/5 and 25 mg/ml) by meceration. Antibacterial activity of the extract wasconducted with agar well diffusion and micro dilution method on the abovementionedstandard strains. Data analysis was performed by one-way ANOVA analysis at P<0. 001. Results: The maximum sensitivity with average diameter of the inhibition zone (13± 0/45mm) was assessed risen from the concentration of 50 mg/ml ETHANOLIC EXTRACT of the plantCalendual officinalis L. flowers of Staphylococcus aureus. Also, the minimum inhibitoryconcentration for Staphylococcus aureus and Enterococcus faecalis was 0. 75 mg/ml. Also, the minimum lethal concentration was 0. 75 mg/ml against Staphylococcus aureus bacteria. Conclusion: The ETHANOLIC EXTRACT of flowering plants CALENDUAL OFFICINALIS L. in springtimeunder laboratory conditions has inhibitory effect against all four strains tested. Therefore, thisextract can be a good alternative for future studies in in vivo to provide antibacterial drugs.

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    APA: Copy

    IMENI, NAZILA, & GHIAMI RAD, MEHDI. (2018). ANTIMICROBIAL EFFECT OF ETHANOLIC EXTRACT OF CALENDUAL OFFICINALIS L. AGAINSTOF STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS, ESCHERICHIA COLI ANDPSEUDOMONAS AERUGINOSA SSTRAINS IN VITRO. ZANKO JOURNAL OF MEDICAL SCIENCES, 19(62 ), 61-69. SID. https://sid.ir/paper/113166/en

    Vancouver: Copy

    IMENI NAZILA, GHIAMI RAD MEHDI. ANTIMICROBIAL EFFECT OF ETHANOLIC EXTRACT OF CALENDUAL OFFICINALIS L. AGAINSTOF STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS, ESCHERICHIA COLI ANDPSEUDOMONAS AERUGINOSA SSTRAINS IN VITRO. ZANKO JOURNAL OF MEDICAL SCIENCES[Internet]. 2018;19(62 ):61-69. Available from: https://sid.ir/paper/113166/en

    IEEE: Copy

    NAZILA IMENI, and MEHDI GHIAMI RAD, “ANTIMICROBIAL EFFECT OF ETHANOLIC EXTRACT OF CALENDUAL OFFICINALIS L. AGAINSTOF STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS, ESCHERICHIA COLI ANDPSEUDOMONAS AERUGINOSA SSTRAINS IN VITRO,” ZANKO JOURNAL OF MEDICAL SCIENCES, vol. 19, no. 62 , pp. 61–69, 2018, [Online]. Available: https://sid.ir/paper/113166/en

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