MOLECULAR MECHANISM OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS DURING INFLAMMATION

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MOHAMMADI ESMAT; GHAEDI KAMRAN; ESMAEILI ABOLGHASEM; RAHGOZAR SOHEILA

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Journal: GENETICS IN THE 3RD MILLENNIUM Year:2011 | Volume:9 | Issue:2 Page(s): 2410-2420

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Information Journal Paper

Title

MOLECULAR MECHANISM OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS DURING INFLAMMATION

Author(s)

MOHAMMADI ESMAT | GHAEDI KAMRAN | ESMAEILI ABOLGHASEM | RAHGOZAR SOHEILA | Issue Writer Certificate

Keywords

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORQ2

INFLAMMATIONQ2

CYTOKINESQ2

Abstract

Inflammation is the normal response of the body to injuries to remove dead cell debris and infections at injury sites and repair the tissue. However, excessive INFLAMMATION is harmful to the body because of its positive feedback and disruption of normal cells. Thus, recruitment of the regulatory mechanisms for modulating the INFLAMMATION is crucial for the body. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORs (PPARs) are ligand-activated transcription factors and members of the nuclear receptor super family. Among these superfamily members, PPARU ia involved in the regulation of numerous cellular processes such as INFLAMMATION. Several activators of PPARU have been known to exert possible roles in immune function through mechanisms such as transactivation of genes that suppress the INFLAMMATION, trans-repression of inflammatory genes, interaction with other receptors that lead to effective suppression of the inflammatory agents. Here in this review article, we describe the molecular events which are triggered by these molecules in elaboration of INFLAMMATION process.

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APA: Copy

MOHAMMADI, ESMAT, GHAEDI, KAMRAN, ESMAEILI, ABOLGHASEM, & RAHGOZAR, SOHEILA. (2011). MOLECULAR MECHANISM OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS DURING INFLAMMATION. GENETICS IN THE 3RD MILLENNIUM, 9(2), 2410-2420. SID. https://sid.ir/paper/117230/en

Vancouver: Copy

MOHAMMADI ESMAT, GHAEDI KAMRAN, ESMAEILI ABOLGHASEM, RAHGOZAR SOHEILA. MOLECULAR MECHANISM OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS DURING INFLAMMATION. GENETICS IN THE 3RD MILLENNIUM[Internet]. 2011;9(2):2410-2420. Available from: https://sid.ir/paper/117230/en

IEEE: Copy

ESMAT MOHAMMADI, KAMRAN GHAEDI, ABOLGHASEM ESMAEILI, and SOHEILA RAHGOZAR, “MOLECULAR MECHANISM OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS DURING INFLAMMATION,” GENETICS IN THE 3RD MILLENNIUM, vol. 9, no. 2, pp. 2410–2420, 2011, [Online]. Available: https://sid.ir/paper/117230/en

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