THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL

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HAJIHASHEMI P.; AZADBAKHT L.; HASHEMIPOR M.; KELISHADI R.; ESMAILLZADEH A.

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Journal: JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY Year:2014 | Volume:9 | Issue:2 Page(s): 19-27

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Title

THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL

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WHOLE GRAINSQ2

METABOLIC PROFILEQ2

OBESITYQ3

OVERWEIGHTQ3

GIRLSQ3

Abstract

Background and objective: Although whole-grain foods have been reported to affect the METABOLIC PROFILE, limited data are available in this regard on children. The present study aimed to determine the effects of whole-grain consumption on fasting blood glucose and lipid profile of OVERWEIGHT or obese children.Materials and methods: This randomized cross-over clinical trial included 44 OVERWEIGHT or obese (BMI>85th percentile for age and sex) GIRLS aged 8-15 years. After a 2-week run-in period, the subjects were randomly assigned to either an intervention or a control group. The subjects in the intervention group were given a list of whole-grain foods (dark bread (sangak and barbari), brown rice, whole-meal biscuits, wheat germ, wheat bran and cornflakes) and asked to choose and consume 50% of their daily grain servings, for 6 weeks, from among whole-grain foods. Those in the control group were given similarly a list of whole-grain foods and asked not to consume any of those foods during the intervention phase of the study. A 4-week washout period was applied following which the subjects were crossed over to the alternate arm for an additional 6 weeks. Fasting blood samples were taken before and after each phase of study for biochemical measurements and METABOLIC PROFILE determination.Results: Mean (±SD) age, body mass index, systolic and diastolic blood pressures of the subjects were 11.2±1.49 years and 23.5±2.5 kg/m2, 111.4±9.7 and 66.4±9.1 mmHg, respectively. After 6 weeks we found significant effects of consuming whole-grain foods on plasma glucose (changes from baseline in the intervention group -1.9 vs.3.8 mg/dL in the control group, P=0.01), serum triglycerides (changes from baseline in the intervention group -16 vs.7 mg/dL in the control group, P=0.01), and serum HDL-cholesterol levels (changes from baseline in the intervention group 6.3 vs. -5.6 mg/dL in the control group, P=0.05). Whole grain intake had no significant effect on serum total and LDL-cholesterol concentrations or blood pressure.Conclusion: This study provides evidence supporting the beneficial effects of consuming whole-grain foods on the serum levels of fasting blood glucose and lipid profile (TG and HDL) in obese or OVERWEIGHT children.

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APA: Copy

HAJIHASHEMI, P., AZADBAKHT, L., HASHEMIPOR, M., KELISHADI, R., & ESMAILLZADEH, A.. (2014). THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 9(2), 19-27. SID. https://sid.ir/paper/121573/en

Vancouver: Copy

HAJIHASHEMI P., AZADBAKHT L., HASHEMIPOR M., KELISHADI R., ESMAILLZADEH A.. THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY[Internet]. 2014;9(2):19-27. Available from: https://sid.ir/paper/121573/en

IEEE: Copy

P. HAJIHASHEMI, L. AZADBAKHT, M. HASHEMIPOR, R. KELISHADI, and A. ESMAILLZADEH, “THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL,” JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, vol. 9, no. 2, pp. 19–27, 2014, [Online]. Available: https://sid.ir/paper/121573/en

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