THE EFFECT OF OLEIC ACID (OMEGA 9) ON SPATIAL LEARNING IN ADULTS MALE RATS

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HOSSEINZADEH Z.; MOAZEDI A.A.; CHINIPARDAZ RAHIM

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Journal: Jundishapur Scientific Medical Journal Year:2007 | Volume:6 | Issue:3 (54) Page(s): 343-351

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Title

THE EFFECT OF OLEIC ACID (OMEGA 9) ON SPATIAL LEARNING IN ADULTS MALE RATS

Author(s)

HOSSEINZADEH Z. | MOAZEDI A.A. | CHINIPARDAZ RAHIM | Issue Writer Certificate

Keywords

SPATIAL LEARNINGQ3

OLEIC ACIDQ3

RATSQ3

T-MAZEQ3

Abstract

Objective: OLEIC ACID (OA) (Omega 9) is an essential constituent of neuronal membrane. This fatty acid is transferred across the placenta and is accumulated in the brain during fetal development. It induces neuronal differentiation during rat brain development and behaves as a neurotrophic factor for neurons, promotes axonal growth, neuronal clustering. However, it role in adulthood has not been finny established. The aim of this study was, therefore, to test the effects of this fatty on SPATIAL LEARNING in adult RATS.Subjects and Methods: Wister adult male RATS were selected and divided randomly, into five groups (n=9). The control group was fed with an ordinary diet and the remaining four groups were fed with a diet containing 10 % OA for 1, 2, 3 and 4 weeks, respectively. The RATS were tested for SPATIAL LEARNING task using T-MAZE over for 9 days based on standard method.Results: The result showed that the RATS fed with 10 % OA in their diet for 4 weeks had a significant increase in special learning relative to other groups (p<0.01).Conclusion: It seems this unsaturated fatty acid increases SPATIAL LEARNING in adulthood and this action may be mediated by increase in the fluidity of membrane nerve cell especially in hippocampus area.

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APA: Copy

HOSSEINZADEH, Z., MOAZEDI, A.A., & CHINIPARDAZ, RAHIM. (2007). THE EFFECT OF OLEIC ACID (OMEGA 9) ON SPATIAL LEARNING IN ADULTS MALE RATS. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 6(3 (54)), 343-351. SID. https://sid.ir/paper/12597/en

Vancouver: Copy

HOSSEINZADEH Z., MOAZEDI A.A., CHINIPARDAZ RAHIM. THE EFFECT OF OLEIC ACID (OMEGA 9) ON SPATIAL LEARNING IN ADULTS MALE RATS. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2007;6(3 (54)):343-351. Available from: https://sid.ir/paper/12597/en

IEEE: Copy

Z. HOSSEINZADEH, A.A. MOAZEDI, and RAHIM CHINIPARDAZ, “THE EFFECT OF OLEIC ACID (OMEGA 9) ON SPATIAL LEARNING IN ADULTS MALE RATS,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 6, no. 3 (54), pp. 343–351, 2007, [Online]. Available: https://sid.ir/paper/12597/en

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