EVALUATION OF SERUM LEVEL OF TESTOSTERONE, DEHYDROPIANDROSTERONE SULPHATE (DHEA-S) PROLACTIN, LUTEINIZING HORMONE (LH) FOLLICLE STIMULATING HORMONE (FSH) IN WOMEN WITH HIRSUTISM

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RAHIMINEZHAD M.; SALEH A.A.S.; JANDAGHI AMIRABADI Y.; SHAYAN Z.

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Journal: Pars Journal of Medical Sciences Year:2008 | Volume:5 | Issue:5 Page(s): 7-13

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Title

EVALUATION OF SERUM LEVEL OF TESTOSTERONE, DEHYDROPIANDROSTERONE SULPHATE (DHEA-S) PROLACTIN, LUTEINIZING HORMONE (LH) FOLLICLE STIMULATING HORMONE (FSH) IN WOMEN WITH HIRSUTISM

Author(s)

RAHIMINEZHAD M. | SALEH A.A.S. | JANDAGHI AMIRABADI Y. | SHAYAN Z. | Issue Writer Certificate

Keywords

HIRSUTISMQ3

TESTOSTERONEQ2

DHEA-SQ3

PROLACTINQ3

LHQ3

FSHQ3

Abstract

Introduction: HIRSUTISM is a common problem in young women that may be, sign of internal glands diseases (eg: ovary, adrenal, hypophysis,...) The aim of this research was measurement of serum level of hormones that produce by these glands in women with HIRSUTISM.Materials and Methods: In this cross-sectional, descriptive research, in all the hirsute women that referred to Dermatology clinic of Jahrom from April 2004 to April 2005 serum level of TESTOSTERONE, Dehydroepiandrosterone-sulphate (DHEA-S), PROLACTIN, Luteinizing hormone (LH) and Follicle-Stimulating Hormone (FSH) was measured with ELISA method.Testosterone> 1.2 ng/ml. DHEA-S > 41 mg/ml, PROLACTIN> 25 ng/ml and LH/FSH>3 was considered abnormal. Data was analysed by chi-square method.Results: Out of 81 patients who was referred, 59 patients (72.8%) had positive FHx of HIRSUTISM and 42 pts (52%) had irregular menstruation. Serum TESTOSTERONE, DHEA-S and PROLACTIN was high in 9.9% (7pts of 71 pts), 12.7% (10 pts of 79pts), 10.1% (8pts of 79pts) respectively and 23.8% (19pts of 80 pts) had LH/FSH>3. High level of serum TESTOSTERONE DHEA-S and PROLACTIN didn't have significant correlation with irregular menstruation (P=.429, .087, .713 respectively), Positive FHx (P= .67, .452, 1.000 respectively) and marital status (P=.684, .73, .707 respectively). LH/FSH>3 had significant correlation with irregular mensturation (P<0.001), But didn't have significant correlation with age (P=0.126), merrital status (p=.784) and positive FHx (P=.648).Overall34pts (42/5%) had at least one abnormality in their laboratory examination (testosteron or DHEA-S or PROLACTINor LH/FSH >3). Conclusion: Out of81 pts, 59 pts (72.8%) had positives FHx of HIRSUTISM so it seems that genetic has significant role for inducing of HIRSUTISM. Manypts with HIRSUTISM [34pts (42.5%)] had at least one hormonal abnormality so as screening tests, measurement of hormones such as TESTOSTERONE, DHEA-S, PROLACTIN, LH and FSH is necessary in pts with HIRSUTISM.

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APA: Copy

RAHIMINEZHAD, M., SALEH, A.A.S., JANDAGHI AMIRABADI, Y., & SHAYAN, Z.. (2008). EVALUATION OF SERUM LEVEL OF TESTOSTERONE, DEHYDROPIANDROSTERONE SULPHATE (DHEA-S) PROLACTIN, LUTEINIZING HORMONE (LH) FOLLICLE STIMULATING HORMONE (FSH) IN WOMEN WITH HIRSUTISM. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 5(5), 7-13. SID. https://sid.ir/paper/130906/en

Vancouver: Copy

RAHIMINEZHAD M., SALEH A.A.S., JANDAGHI AMIRABADI Y., SHAYAN Z.. EVALUATION OF SERUM LEVEL OF TESTOSTERONE, DEHYDROPIANDROSTERONE SULPHATE (DHEA-S) PROLACTIN, LUTEINIZING HORMONE (LH) FOLLICLE STIMULATING HORMONE (FSH) IN WOMEN WITH HIRSUTISM. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2008;5(5):7-13. Available from: https://sid.ir/paper/130906/en

IEEE: Copy

M. RAHIMINEZHAD, A.A.S. SALEH, Y. JANDAGHI AMIRABADI, and Z. SHAYAN, “EVALUATION OF SERUM LEVEL OF TESTOSTERONE, DEHYDROPIANDROSTERONE SULPHATE (DHEA-S) PROLACTIN, LUTEINIZING HORMONE (LH) FOLLICLE STIMULATING HORMONE (FSH) IN WOMEN WITH HIRSUTISM,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 5, no. 5, pp. 7–13, 2008, [Online]. Available: https://sid.ir/paper/130906/en

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