EFFECTS OF ESSENTIAL OIL AND EXTRACT OF THYMUS VULGARIS, ZATARIA MULTIFLORA AND EUGENIA CARYOPHILATA ON VERO, HELA, HEPII CELL LINES BY MTT ASSAY

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RAHIMIFARD N.; PAKZAD S.R.; SHOEYBI SH.; HEDAYATI M.R.; HAJI MAHDIPOUR H.; MOTAHARINIA V.; MEHRAFSHAN L.; JAVADI AIDA; PIRALI HAMEDANI M.

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Journal: Journal of Medicinal Plants Year:2009 | Volume:8 | Issue:30 Page(s): 152-156

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Title

EFFECTS OF ESSENTIAL OIL AND EXTRACT OF THYMUS VULGARIS, ZATARIA MULTIFLORA AND EUGENIA CARYOPHILATA ON VERO, HELA, HEPII CELL LINES BY MTT ASSAY

Author(s)

Keywords

EUGENIA CARYOPHYLLATAQ3

THYMUS VULGARISQ2

ZATARIA MULTIFLORAQ3

CYTOPATHIC EFFECTSQ3

MTT ASSAYQ3

VEROQ3

HELAQ3

HEP2 CELL LINESQ3

Abstract

Background: Natural flavors essential oils are almost present in various food stuffs, cosmetic and pharmaceutical products. Safety assessment of these food additives should be seriously considered as long as their due wide applications are favorable.Objective: Natural flavors essential oils are widely used in various foods, cosmetic and pharmaceutical products. These kinds of additives are applied as colors, preservatives, aroma, antioxidant agents and tasting agents. In some cases, it may happen that the large use of some of these additives may accompany with some concerns and unwanted toxic disturbs. Methods: In this study, Concentrations of 24, 12, 6, 3, 1.5, 0.75, 0.375, 0.1875ppm (µg/ml) of three essential oils, EUGENIA CARYOPHYLLATA, THYMUS VULGARIS and ZATARIA MULTIFLORA, were tested in MTT ASSAY with three cell line VERO, Hep2, HELA.Results: All three Essential oils and extracts were shown cytopathological effects on three cell lines in MTT ASSAY in at least 0.04 µg/ml to maximum 3.0 µg/ml concentrations.Conclusion: Based on obtained results, all studied essential oils and extracts may have cytopathologic effect in specific concentrations so suggested using of this compound should be performed with considering their proper concentration and more safety studies on them.

Cites

CYTOTOXIC EFFECTS OF ESSENTIAL OILS AND EXTRACTS OF SOME MENTHA SPECIES ON VERO, HELA AND HEP2 CELL LINES

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APA: Copy

RAHIMIFARD, N., PAKZAD, S.R., SHOEYBI, SH., HEDAYATI, M.R., HAJI MAHDIPOUR, H., MOTAHARINIA, V., MEHRAFSHAN, L., JAVADI, AIDA, & PIRALI HAMEDANI, M.. (2009). EFFECTS OF ESSENTIAL OIL AND EXTRACT OF THYMUS VULGARIS, ZATARIA MULTIFLORA AND EUGENIA CARYOPHILATA ON VERO, HELA, HEPII CELL LINES BY MTT ASSAY. JOURNAL OF MEDICINAL PLANTS, 8(30), 152-156. SID. https://sid.ir/paper/15602/en

Vancouver: Copy

RAHIMIFARD N., PAKZAD S.R., SHOEYBI SH., HEDAYATI M.R., HAJI MAHDIPOUR H., MOTAHARINIA V., MEHRAFSHAN L., JAVADI AIDA, PIRALI HAMEDANI M.. EFFECTS OF ESSENTIAL OIL AND EXTRACT OF THYMUS VULGARIS, ZATARIA MULTIFLORA AND EUGENIA CARYOPHILATA ON VERO, HELA, HEPII CELL LINES BY MTT ASSAY. JOURNAL OF MEDICINAL PLANTS[Internet]. 2009;8(30):152-156. Available from: https://sid.ir/paper/15602/en

IEEE: Copy

N. RAHIMIFARD, S.R. PAKZAD, SH. SHOEYBI, M.R. HEDAYATI, H. HAJI MAHDIPOUR, V. MOTAHARINIA, L. MEHRAFSHAN, AIDA JAVADI, and M. PIRALI HAMEDANI, “EFFECTS OF ESSENTIAL OIL AND EXTRACT OF THYMUS VULGARIS, ZATARIA MULTIFLORA AND EUGENIA CARYOPHILATA ON VERO, HELA, HEPII CELL LINES BY MTT ASSAY,” JOURNAL OF MEDICINAL PLANTS, vol. 8, no. 30, pp. 152–156, 2009, [Online]. Available: https://sid.ir/paper/15602/en

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