EFFECTS OF SPERMIOGENIC DEFECTS ON FERTILIZATION AND PREGNANCY RATE IN IVF PATIENTS

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TAVALAEI M.; RAZAVI SHAHNAZ; NASRESFAHANI MOHAMMAD HOSSEIN

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Journal: Cell Journal (Yakhteh) Year:2007 | Volume:9 | Issue:2 (34) Page(s): 103-110

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Title

EFFECTS OF SPERMIOGENIC DEFECTS ON FERTILIZATION AND PREGNANCY RATE IN IVF PATIENTS

Author(s)

TAVALAEI M. | RAZAVI SHAHNAZ | NASRESFAHANI MOHAMMAD HOSSEIN | Issue Writer Certificate

Keywords

CHROMOMYCIN A3 (CMA3)Q2

GELATINOLYSIS TESTQ2

PREGNANCYQ2

IN VITRO FERTILIZATIONQ3

Abstract

Objective: The objective of this study was to evaluate the relationship between spermiogenic defects such as protamine deficiency, and acrosomal integrity with fertilization and PREGNANCY rate in IVF patients.Materials and Methods: Density, motility and morpology of semen samples from 70 infertile couples undergoing IVF at Isfahan Fertility and Infertility center were analyzed according to WHO criteria. Protamine deficiency and acrosin activity were assessed by Chromomycin A3 (CMA3) and GELATINOLYSIS TEST. Statistical analysis was carried out using the Statistical Package for the Social Studies (SPSS 11.5) and P-value lower than 0.05 was considered to be significant.Results: CMA3 positivity, percentage halo formation, means halo diameter and sperm morphology showed a significant correlation with fertilization rate. The rate of halo formation and mean halo diameter showed a significant correlation with CMA3 positivity. None of the parameters were significantly different between pregnant and non - pregnant patients. However, the rate of halo formation showed a closely significant difference (r=0.306; P=0.058).Conclusion: The results of the present study indicate that sperm acrosomal integrity assessed by percentage halo formation has profound effects on PREGNANCY outcome in IVF procedure.

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APA: Copy

TAVALAEI, M., RAZAVI, SHAHNAZ, & NASRESFAHANI, MOHAMMAD HOSSEIN. (2007). EFFECTS OF SPERMIOGENIC DEFECTS ON FERTILIZATION AND PREGNANCY RATE IN IVF PATIENTS. CELL JOURNAL (YAKHTEH), 9(2 (34)), 103-110. SID. https://sid.ir/paper/16171/en

Vancouver: Copy

TAVALAEI M., RAZAVI SHAHNAZ, NASRESFAHANI MOHAMMAD HOSSEIN. EFFECTS OF SPERMIOGENIC DEFECTS ON FERTILIZATION AND PREGNANCY RATE IN IVF PATIENTS. CELL JOURNAL (YAKHTEH)[Internet]. 2007;9(2 (34)):103-110. Available from: https://sid.ir/paper/16171/en

IEEE: Copy

M. TAVALAEI, SHAHNAZ RAZAVI, and MOHAMMAD HOSSEIN NASRESFAHANI, “EFFECTS OF SPERMIOGENIC DEFECTS ON FERTILIZATION AND PREGNANCY RATE IN IVF PATIENTS,” CELL JOURNAL (YAKHTEH), vol. 9, no. 2 (34), pp. 103–110, 2007, [Online]. Available: https://sid.ir/paper/16171/en

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