COMPARISON OF MEAN VALUES OF BILAG INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS WITH AND WITHOUT METABOLIC SYNDROME

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SEYED BONAKDAR ZAHRA; TANSAZ J.

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Journal: Researcher Bulletin of Medical Sciences Year:2009 | Volume:13 | Issue:5 (65) Page(s): 417-423

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Title

COMPARISON OF MEAN VALUES OF BILAG INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS WITH AND WITHOUT METABOLIC SYNDROME

Author(s)

SEYED BONAKDAR ZAHRA | TANSAZ J. | Issue Writer Certificate

Keywords

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)Q2

METABOLIC SYNDROMEQ3

BILAG INDEXQ3

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease that involves many people for long time. SLE affects several organs such as skin, kidney and joints. A substantial number of SLE patients, also suffer from hypertension and are susceptible for insulin resistance and METABOLIC SYNDROME. The aim of present study is to compare SLE activity in SLE patients with and without METABOLIC SYNDROME.Materials and Methods: One hundred patients enrolled the study. 51 had METABOLIC SYNDROME while 49 did not. According to British Isles Lupus Assessment Group (BILAG) Index, Lupus activity was calculated for these two groups and means of Lupus activity score were compared.Results: Mean of lupus activity score was significantly more in METABOLIC SYNDROME group (2.14±1.73 vs. 5.90±3.37 P<0.001). Patients were also compared for serum creatinin, history of corticosteroid therapy or Cyclophosphamide administration and elevated ESR levels. All of these parameters were significantly higher in patients with METABOLIC SYNDROME.Conclusion: We concluded that Lupus activity in patients afflicted by METABOLIC SYNDROME is more than patients without this syndrome. There are many probable reasons for this statement such as various types of SLE treatments, similar inflammatory nature of METABOLIC SYNDROME and SLE, further susceptibility of insulin resistance in lupus patients or complications of Lupus flare up.

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APA: Copy

SEYED BONAKDAR, ZAHRA, & TANSAZ, J.. (2009). COMPARISON OF MEAN VALUES OF BILAG INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS WITH AND WITHOUT METABOLIC SYNDROME. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 13(5 (65)), 417-423. SID. https://sid.ir/paper/18281/en

Vancouver: Copy

SEYED BONAKDAR ZAHRA, TANSAZ J.. COMPARISON OF MEAN VALUES OF BILAG INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS WITH AND WITHOUT METABOLIC SYNDROME. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2009;13(5 (65)):417-423. Available from: https://sid.ir/paper/18281/en

IEEE: Copy

ZAHRA SEYED BONAKDAR, and J. TANSAZ, “COMPARISON OF MEAN VALUES OF BILAG INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS WITH AND WITHOUT METABOLIC SYNDROME,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 13, no. 5 (65), pp. 417–423, 2009, [Online]. Available: https://sid.ir/paper/18281/en

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